STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16685.1COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR003660: IPR004358: IPR003661: IPR 003594; KEGG: noc:Noc_0675 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Periplasmic sensor signal transduction histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoac [...] (513 aa)    
Predicted Functional Partners:
ADW16686.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: glo:Glov_0050 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Two-component response transcriptional regulator (OmpR family); PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.972
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
    
 0.960
ADW19026.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR003660: IPR003661: IPR 003594: IPR004358; KEGG: gbm:Gbem_3181 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SPTR: Hpt sensor hybrid histidine kinase; [...]
 
 
0.940
ADW17015.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013767: IPR003661: IPR003594: IPR001789: IPR 004358: IPR000014: IPR001610: IPR005467: IPR000700; KEGG: dps:DP1518 Ntr family two-component system sensory/regulatory protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain contain [...]
 
 
 0.937
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
 
 
0.911
ADW19133.1
Multi-sensor hybrid histidine kinase; COGs: COG3614 periplasmic ligand-binding sensor domain; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 006189: IPR013767: IPR013656: IPR003594: IPR004358: IPR001610; KEGG: gsu:GSU2816 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; CHASE domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: PAS/PAC sensor [...]
 
 
 0.910
ADW17352.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 003661: IPR003594: IPR013767; KEGG: dak:DaAHT2_1107 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Response regulator receiver; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90 [...]
 
 
 0.906
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
 
 
0.902
ADW18650.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR003660: IPR000014: IPR001610: IPR 003661: IPR003594: IPR001789: IPR005467: IPR000700: IPR008207:I PR013655; KEGG: dba:Dbac_2628 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain contai [...]
 
 
0.893
ADW17371.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: dat:HRM2_10430 transcriptional regulatory protein; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: DNA-binding response regulator ArlR; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
 0.889
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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