close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16698.1COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518: IPR018223; KEGG: dak:DaAHT2_2212 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase. (399 aa)    
Predicted Functional Partners:
ADW16699.1
COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049: IPR003031: IPR000362: IPR020557; KEGG: dak:DaAHT2_2213 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
 
 0.999
ADW16697.1
COGs: COG0078 Ornithine carbamoyltransferase; InterPro IPR002292: IPR006130: IPR006132: IPR006131; KEGG: dps:DP0437 ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Ornithine carbamoyltransferase; SPTR: Ornithine carbamoyltransferase; TIGRFAM: ornithine carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase.
 
 
 0.998
carB
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005483: IPR011761: IPR005481: IPR005479: IPR 005480: IPR011607: IPR006275; KEGG: dps:DP3096 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Probable carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding dom [...]
 
 
 0.982
ADW19423.1
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005481: IPR005479: IPR005480: IPR011607: IPR 005483: IPR006275: IPR011761; KEGG: sat:SYN_02589 carbamoyl phosphate synthase large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-l [...]
 
 
 0.980
ADW16695.1
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR004636: IPR005814; KEGG: dak:DaAHT2_2210 acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine and succinylornithine aminotransferase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases.
 
 
 0.962
ADW16694.1
COGs: COG0548 Acetylglutamate kinase; InterPro IPR011148: IPR001057: IPR004662: IPR001048; KEGG: dps:DP0439 acetylglutamate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: Acetylglutamate kinase; SPTR: Acetylglutamate kinase; TIGRFAM: acetylglutamate kinase; PFAM: Amino acid kinase family; TIGRFAM: acetylglutamate kinase.
  
  
 0.958
ADW17120.1
N-acetyl-gamma-glutamyl-phosphate reductase; COGs: COG0002 Acetylglutamate semialdehyde dehydrogenase; InterPro IPR000534: IPR012280: IPR000706; KEGG: dps:DP1325 N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; PRIAM: N-acetyl-gamma-glutamyl-phosphate reductase; SPTR: N-acetyl-gamma-glutamyl-phosphate reductase; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: N-acetyl-gamma-gluta [...]
 
  
 0.950
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.935
ADW17102.1
COGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR001317: IPR011702: IPR006220: IPR017926: IPR 002474: IPR000991: IPR006274; KEGG: dps:DP3095 carbamoyl phosphate synthase small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; SPTR: Probable carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit.
  
 
 0.931
ADW17825.1
COGs: COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase); InterPro IPR002813; KEGG: dps:DP2741 bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein; PFAM: arginine biosynthesis protein ArgJ; PRIAM: Amino-acid N-acetyltransferase; SPTR: Arginine biosynthesis bifunctional protein ArgJ; TIGRFAM: arginine biosynthesis bifunctional protein ArgJ; PFAM: ArgJ family; TIGRFAM: glutamate N-acetyltransferase/amino-acid acetyltransferase.
  
  
 0.930
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.