STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16704.12-amino-4-hydroxy-6-hydroxymethyldihydropteridin epyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: dps:DP0430 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK; SPTR: Probable 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM:2-amino-4-hydroxy-6-hydroxymethyldihydropte ridinepyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine p [...] (180 aa)    
Predicted Functional Partners:
ADW17105.1
COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489: IPR006390; KEGG: dak:DaAHT2_0903 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase.
 
 0.999
ADW16810.1
COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: pca:Pcar_1589 beta-lactamase superfamily hydrolase; SPTR: Metal-dependent hydrolase of the beta-lactamase superfamily II; PFAM: Metallo-beta-lactamase superfamily.
     
  0.900
ADW17717.1
FolC bifunctional protein; COGs: COG0285 Folylpolyglutamate synthase; InterProIPR001645: IPR013221: IPR004101: IPR018486: IPR 018109; KEGG: dak:DaAHT2_1269 FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; PRIAM: Tetrahydrofolate synthase; SPTR: FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase.
  
 0.864
ADW16847.1
Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646: IPR006674: IPR006675: IPR003607; KEGG: dak:DaAHT2_1316 polynucleotide adenylyltransferase/metal dependent phosphohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; Poly A polymerase head domain; TIGR [...]
  
    0.813
ADW18907.1
poly(A) polymerase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646: IPR010206; KEGG: dak:DaAHT2_1536 polynucleotide adenylyltransferase; PFAM: Polynucleotide adenylyltransferase region; SPTR: Poly(A) polymerase, PcnB; TIGRFAM: poly(A) polymerase; PFAM: Poly A polymerase head domain; TIGRFAM: poly(A) polymerase.
  
    0.813
ADW19316.1
COGs: COG0413 Ketopantoate hydroxymethyltransferase; InterPro IPR003700; KEGG: hmo:HM1_2754 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; PRIAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; SPTR: 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase.
 
  
 0.765
ADW19426.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; COGs: COG0127 Xanthosine triphosphate pyrophosphatase; InterPro IPR020922: IPR002637; KEGG: dps:DP0707 nucleoside-triphosphatase; PFAM: Ham1 family protein; SPTR: Nucleoside-triphosphatase; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family.
  
  
 0.694
ADW16703.1
COGs: COG0289 Dihydrodipicolinate reductase; InterPro IPR011770: IPR000846; KEGG: dak:DaAHT2_2218 dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase; PRIAM: Dihydrodipicolinate reductase; SPTR: Dihydrodipicolinate reductase; TIGRFAM: dihydrodipicolinate reductase; PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase.
     
 0.676
ADW16706.1
Transaldolase; COGs: COG0176 Transaldolase; InterPro IPR004731: IPR001585: IPR018225; KEGG: dak:DaAHT2_2221 transaldolase; PFAM: Transaldolase; SPTR: Transaldolase; TIGRFAM: transaldolase; PFAM: Transaldolase; TIGRFAM: fructose-6-phosphate aldolase, TalC/MipB family.
     
 0.647
ADW16708.1
CDP-diacylglycerol/glycerol-3-phosphate3-phospha tidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR004570: IPR000462; KEGG: dps:DP0426 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: Probable CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.
     
 0.645
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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