Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW16749.1COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: dak:DaAHT2_2000 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein. (239 aa)    
Predicted Functional Partners:
ADW18470.1
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004477: IPR004797; KEGG: dps:DP1704 ComE operon protein 3; PFAM: ComEC/Rec2-related protein; SPTR: Related to ComE operon protein 3; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
 
  
 0.961
ADW19070.1
DNA protecting protein DprA; COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: dak:DaAHT2_2319 DNA protecting protein DprA; PFAM: SMF family protein; SPTR: SMF protein; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA.
 
 
 0.948
ADW17528.1
Mg chelatase, subunit ChlI; COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482: IPR001208: IPR000523: IPR003593; KEGG: dak:DaAHT2_1394 Mg chelatase, subunit ChlI; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase; SPTR: Putative enzyme (N-terminal); transcriptional regulator with P-loop containing NTP hydrolase domain (C-terminal)(YifB); TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: Mg chelatase-related protein.
 
  
 0.849
ADW18324.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR003099: IPR002912; KEGG: dps:DP2275 P-protein; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Prephenate dehydrogenase; SPTR: Related to P-protein; PFAM: Prephenate dehydratase; Prephenate dehydrogenase; ACT domain.
  
    0.815
ADW18524.1
Uncharacterized protein family UPF0102; COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: dak:DaAHT2_1166 protein of unknown function UPF0102; PFAM: Uncharacterised protein family UPF0102; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: conserved hypothetical protein TIGR00252.
 
    0.793
ADW16818.1
COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR006076: IPR002937: IPR004572; KEGG: dps:DP0277 protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; PRIAM: Protoporphyrinogen oxidase; SPTR: Related to protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; FAD dependent oxidoreductase; TIGRFAM: protoporphyrinogen oxidase.
  
    0.792
ADW16726.1
ABC transporter related protein; COGs: COG1134 ABC-type polysaccharide/polyol phosphate transport system ATPase component; InterPro IPR003439: IPR003593; KEGG: nhl:Nhal_3669 ABC transporter related protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC transporter related protein; PFAM: ABC transporter.
   
    0.778
ADW18363.1
COGs: COG1558 Flagellar basal body rod protein; InterPro IPR001444: IPR010930: IPR019776: IPR006299; KEGG: dps:DP2654 flagellar basal body rod protein (FlgC); PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: Probable flagellar basal body rod protein (FlgC); TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgC.
   
   0.776
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
  
    0.775
ADW16750.1
COGs: COG0538 Isocitrate dehydrogenase; InterPro IPR004439: IPR001804: IPR019818; KEGG: hmo:HM1_1471 isocitrate dehydrogenase, nADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; SPTR: Isocitrate dehydrogenase [NADP]; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type.
       0.765
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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