STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16758.1Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR013217; KEGG: dat:HRM2_20450 two component protein (cAMP receptor domain/SAM dependent regulatory domain); PFAM: cyclic nucleotide-binding; Methyltransferase type 12; SMART: cyclic nucleotide-binding; SPTR: Two component protein (CAMP receptor domain/SAM dependent regulatory domain); PFAM: Putative lysophospholipase; Cyclic nucleotide-binding domain. (504 aa)    
Predicted Functional Partners:
ADW18966.1
Adenylate/guanylate cyclase with GAF sensor(s); COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054: IPR003018; KEGG: dal:Dalk_4220 adenylate/guanylate cyclase with GAF sensor(s); PFAM: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase with GAF sensor(S); manually curated; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain.
 
 0.858
ADW16757.1
Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR000014: IPR013767: IPR006674: IPR003607; KEGG: dat:HRM2_20440 two component protein (transcriptional response regulator/sensory box); PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold domain protein; SMART: metal-dependent phosphohydrolase HD region; PAS domain containing protein; SPTR: Two component protein (Transcriptional response regulator/sensory box); TIGRFAM: PAS sensor protein; PFAM: HD domain; PAS fold; TIGRFAM: PAS domain S-box.
 
 
 
 0.846
ADW16756.1
Putative PAS/PAC sensor protein; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR000014: IPR013767: IPR006674; KEGG: dat:HRM2_20440 two component protein (transcriptional response regulator/sensory box); PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold domain protein; SPTR: Two component protein (Transcriptional response regulator/sensory box); TIGRFAM: PAS sensor protein; PFAM: HD domain; PAS fold; TIGRFAM: PAS domain S-box.
 
 
 
 0.818
ADW18429.1
Hypothetical protein; InterPro IPR022265; KEGG: dat:HRM2_13290 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: hypothetical protein; TIGRFAM: conserved hypothetical protein TIGR03790.
  
 
   0.817
ADW18844.1
MIP family channel protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425: IPR012269; KEGG: cli:Clim_1151 MIP family channel protein; PFAM: major intrinsic protein; SPTR: MIP family channel protein; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins.
   
 0.756
ADW17329.1
KEGG: gme:Gmet_1200 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Lecithin:cholesterol acyltransferase.
  
     0.751
ADW17526.1
preQ(0) biosynthesis protein QueD; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: dak:DaAHT2_0938 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
    
  0.735
ADW17152.1
Abortive infection protein; InterPro IPR003675; KEGG: dat:HRM2_19830 hypothetical protein; PFAM: Abortive infection protein; SPTR: Putative uncharacterized protein; PFAM: CAAX amino terminal protease family; TIGRFAM: CAAX prenyl protease-related protein.
  
     0.718
ADW16859.1
Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: dat:HRM2_08300 ABC-type transporter, permease protein; PFAM: protein of unknown function DUF214; SPTR: ABC-type transporter, permease protein; PFAM: Predicted permease.
  
    0.694
ADW17759.1
Peptidase M15A; COGs: COG3108 conserved hypothetical protein; InterPro IPR013230; KEGG: sfu:Sfum_2869 hypothetical protein; PFAM: Peptidase M15A; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF882).
  
     0.691
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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