Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ADW16772.1Peptidase M24; COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR001714: IPR000587: IPR000994: IPR001131; KEGG: dps:DP0126 Xaa-Pro dipeptidase; PFAM: peptidase M24; creatinase; SPTR: Peptidase M24; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain. (368 aa)    
Predicted Functional Partners:
ADW16773.1
KEGG: dps:DP0125 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.803
ADW16771.1
PhoH family protein; COGs: COG1875 ATPase related to phosphate starvation-inducible protein PhoH; InterPro IPR003714: IPR006596; KEGG: gsu:GSU1866 PhoH family protein; PFAM: PhoH family protein; SMART: Nucleotide binding protein PINc; SPTR: PhoH family protein; PFAM: PhoH-like protein.
       0.682
ADW16770.1
KEGG: dps:DP0127 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.662
ADW16774.1
Sun protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR004573: IPR006027: IPR001678: IPR018314; KEGG: dak:DaAHT2_2304 sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Fmu, rRNA SAM-dependent methyltransferase; TIGRFAM: sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB.
     
 0.621
ADW16769.1
COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR014732: IPR001754: IPR018089; KEGG: dak:DaAHT2_2202 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; PRIAM: Orotidine-5'-phosphate decarboxylase; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 1.
       0.584
ADW19050.1
Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667: IPR003156; KEGG: dak:DaAHT2_1878 phosphoesterase RecJ domain protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Phosphoesterase, RecJ-like:Phosphoesterase, DHHA1; PFAM: DHH family; DHHA1 domain.
 
     0.551
ADW19474.1
Peptidase M16C associated domain protein; COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR011765: IPR007863: IPR013578; KEGG: dps:DP0121 zinc metalloprotease; PFAM: Peptidase M16C associated domain protein; peptidase M16 domain protein; SPTR: Related to zinc metalloprotease; PFAM: Peptidase M16C associated; Peptidase M16 inactive domain; Insulinase (Peptidase family M16).
   
 
 0.546
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
 
   
 0.538
ADW16768.1
COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: dps:DP0881 NADPH-oxidoreductase; PFAM: nitroreductase; SPTR: Related to NADPH-oxidoreductase; PFAM: Nitroreductase family.
  
  
 0.525
ADW17653.1
Dihydrolipoyllysine-residue acetyltransferase; COGs: COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089: IPR004167: IPR001078; KEGG: gur:Gura_1611 branched-chain alpha-keto acid dehydrogenase subunit E2; PFAM: catalytic domain-containing protein of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; PRIAM: Dihydrolipoyllysine-residue acetyltransferase; SPTR: Catalytic domain of components of various dehydrogenase complexes; PFAM: 2-oxoacid dehyd [...]
 
 
 
 0.492
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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