STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16818.1COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR006076: IPR002937: IPR004572; KEGG: dps:DP0277 protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; PRIAM: Protoporphyrinogen oxidase; SPTR: Related to protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; FAD dependent oxidoreductase; TIGRFAM: protoporphyrinogen oxidase. (490 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.997
ADW16925.1
Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase.
 
 
 0.996
ADW19242.1
Protoporphyrin IX magnesium-chelatase; COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR000523: IPR002035: IPR003593; KEGG: ppd:Ppro_1261 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; von Willebrand factor type A; PRIAM: Magnesium chelatase; SMART: von Willebrand factor type A; AAA ATPase; SPTR: Protoporphyrin IX magnesium-chelatase; PFAM: Magnesium chelatase, subunit ChlI; von Willebrand factor type A domain; TIGRFAM: cobaltochelatase subunit.
  
 
 0.946
ADW19241.1
Protoporphyrin IX magnesium-chelatase; COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR000523: IPR003593; KEGG: ppd:Ppro_1262 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; PRIAM: Magnesium chelatase; SMART: AAA ATPase; SPTR: Protoporphyrin IX magnesium-chelatase; PFAM: Magnesium chelatase, subunit ChlI.
   
 
 0.921
ADW16749.1
COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: dak:DaAHT2_2000 phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Phosphoribosyltransferase; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein.
  
    0.818
ADW18324.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR003099: IPR002912; KEGG: dps:DP2275 P-protein; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Prephenate dehydrogenase; SPTR: Related to P-protein; PFAM: Prephenate dehydratase; Prephenate dehydrogenase; ACT domain.
 
    0.682
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
       0.577
ADW18711.1
Hydroxymethylbilane synthase; COGs: COG0181 Porphobilinogen deaminase; InterPro IPR000860; KEGG: dak:DaAHT2_0535 porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; SPTR: Porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase.
 
  
 0.529
cobA
COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366: IPR003043: IPR000878: IPR003754; KEGG: dps:DP1734 uroporphyrinogen III synthase/methyltransferase (HemD+CobA); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Probable uroporphyrinogen III synthase/methyltransferase (HemD+CobA); TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
  
  
 0.527
ADW17136.1
Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: dps:DP2824 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
  
  
 0.489
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.