STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
ADW16827.1Restriction modification system DNA specificity domain protein; COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: ect:ECIAI39_4817 type I restriction enzyme EcoAI specificity protein (S protein) (S.EcoAI); PFAM: restriction modification system DNA specificity domain; SPTR: Type I restriction-modification system, S subunit, putative; PFAM: Type I restriction modification DNA specificity domain. (521 aa)    
Predicted Functional Partners:
ADW16828.1
Site-specific DNA-methyltransferase (adenine-specific); COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR003356: IPR002296: IPR002052; KEGG: ana:alr3620 type I restriction modification enzyme M subunit; PFAM: N-6 DNA methylase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Putative restriction modification enzyme M subunit; PFAM: N-6 DNA Methylase; HsdM N-terminal domain.
 
 0.998
ADW18589.1
Protein of unknown function DUF450; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR002296: IPR007409: IPR003356; KEGG: gur:Gura_3600 N-6 DNA methylase; PFAM: protein of unknown function DUF450; N-6 DNA methylase; SPTR: N-6 DNA methylase; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); N-6 DNA Methylase.
 
 
 0.967
ADW16829.1
COGs: COG4096 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterProIPR007409: IPR006935: IPR013670: IPR014001: IPR 014021: IPR001650; KEGG: pnu:Pnuc_1134 EcoEI R domain-containing protein; PFAM: EcoEI R domain protein; type III restriction protein res subunit; protein of unknown function DUF450; PRIAM: Type I site-specific deoxyribonuclease; SMART: DEAD-like helicase; SPTR: EcoEI R, C-terminal domain protein; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); EcoEI R protein C-terminal; Type III restriction enzyme, res s [...]
 
 
 0.961
ADW16440.1
N-6 DNA methylase; COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR002052: IPR002296: IPR003356; KEGG: dze:Dd1591_4253 N-6 DNA methylase; PFAM: N-6 DNA methylase; SPTR: N-6 DNA methylase; PFAM: N-6 DNA Methylase; HsdM N-terminal domain.
 
 
 0.949
ADW16445.1
Protein of unknown function DUF450; COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR014001: IPR007409: IPR006935; KEGG: dze:Dd1591_4250 protein of unknown function DUF450; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase; SPTR: Putative uncharacterized protein; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type III restriction enzyme, res subunit.
  
  
 0.845
ADW17183.1
KEGG: sde:Sde_0444 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF3644).
 
    0.747
ADW17645.1
Filamentation induced by cAMP protein Fic; COGs: COG3943 Virulence protein; InterPro IPR003812; KEGG: rrs:RoseRS_0280 death-on-curing protein; PFAM: filamentation induced by cAMP protein Fic; SPTR: Death-on-curing protein; PFAM: Fic/DOC family.
  
    0.541
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
   
 
 0.504
ADW16441.1
COGs: COG3943 Virulence protein; InterPro IPR011204; KEGG: lch:Lcho_4168 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.500
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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