STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16844.1Iron (metal) dependent repressor, DtxR family; COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: dps:DP2966 iron-dependent repressor; PFAM: iron dependent repressor; SMART: iron dependent repressor; SPTR: Probable iron-dependent repressor; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain. (169 aa)    
Predicted Functional Partners:
ADW19335.1
NADH ubiquinone oxidoreductase 20 kDa subunit; COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: dps:DP1042 hydrogenase, component I-formate hydrogenlyase subunit 7; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; SPTR: Related to hydrogenase, component I-formate hydrogenlyase subunit 7; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
    
   0.704
ADW16846.1
Thiamine biosynthesis protein; COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR020536; KEGG: dps:DP2965 hypothetical protein; PFAM: Thiamine biosynthesis protein-like; SPTR: Thiamine biosynthesis protein; PFAM: Thiamine biosynthesis protein (ThiI).
       0.584
ADW16845.1
Sigma 54 interacting domain protein; COGs: COG0497 ATPase involved in DNA repair; InterPro IPR003395: IPR004604: IPR002078; KEGG: dak:DaAHT2_0696 DNA repair protein RecN; PFAM: SMC domain protein; SPTR: DNA repair protein RecN; TIGRFAM: DNA repair protein RecN; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN.
       0.556
ADW16847.1
Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646: IPR006674: IPR006675: IPR003607; KEGG: dak:DaAHT2_1316 polynucleotide adenylyltransferase/metal dependent phosphohydrolase; PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Polynucleotide adenylyltransferase/metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; Poly A polymerase head domain; TIGR [...]
       0.549
ADW16848.1
COGs: COG0293 23S rRNA methylase; InterPro IPR002877: IPR016448; KEGG: dps:DP2909 ribosomal RNA methyltransferase (FtsJ); PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; SPTR: Ribosomal RNA large subunit methyltransferase E; PFAM: FtsJ-like methyltransferase; TIGRFAM: cell division protein FtsJ.
       0.549
tpx
Thiol peroxidase (atypical 2-Cys peroxiredoxin); Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily.
  
  
 0.514
ADW16850.1
Crossover junction endodeoxyribonuclease RuvC; COGs: COG0817 Holliday junction resolvasome endonuclease subunit; InterPro IPR002176: IPR020563; KEGG: lpn:lpg1287 Holliday junction resolvase; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease ruvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC.
     
 0.498
ADW16843.1
General secretion pathway protein F; COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076: IPR003004: IPR011850: IPR001992; KEGG: dol:Dole_1045 general secretion pathway protein F; PFAM: Type II secretion system F domain; SPTR: General secretion pathway protein F; TIGRFAM: general secretion pathway protein F; PFAM: Bacterial type II secretion system protein F domain; TIGRFAM: general secretion pathway protein F.
       0.496
ADW16432.1
ABC-3 protein; COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: dds:Ddes_1010 ABC-3 protein; PFAM: ABC-3 protein; SPTR: ABC-3 protein; PFAM: ABC 3 transport family.
  
  
 0.463
ADW16434.1
Periplasmic solute binding protein; COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: dds:Ddes_1008 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: Periplasmic solute binding protein; PFAM: Periplasmic solute binding protein family.
  
  
 0.460
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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