Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW16846.1Thiamine biosynthesis protein; COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR020536; KEGG: dps:DP2965 hypothetical protein; PFAM: Thiamine biosynthesis protein-like; SPTR: Thiamine biosynthesis protein; PFAM: Thiamine biosynthesis protein (ThiI). (347 aa)    
Predicted Functional Partners:
ADW17211.1
Sulfur relay protein, TusE/DsrC/DsvC family; COGs: COG2920 Dissimilatory sulfite reductase (desulfoviridin) gamma subunit; InterPro IPR007453; KEGG: aba:Acid345_0635 DsrC-like protein; PFAM: DsrC family protein; SPTR: DsrC-like protein; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC like protein; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family.
   
 0.918
ADW17212.1
Sulfur relay protein, TusE/DsrC/DsvC family; COGs: COG2920 Dissimilatory sulfite reductase (desulfoviridin) gamma subunit; InterPro IPR007453; KEGG: adg:Adeg_0035 sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC family protein; SPTR: Sulfur relay protein, TusE/DsrC/DsvC family; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family; PFAM: DsrC like protein; TIGRFAM: sulfur relay protein, TusE/DsrC/DsvC family.
   
 0.918
rplM
LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
 0.917
ADW16974.1
COGs: COG0198 Ribosomal protein L24; InterPro IPR005824: IPR003256: IPR005825; KEGG: dps:DP1135 50S ribosomal protein L24; PFAM: KOW domain protein; SMART: KOW domain protein; SPTR: 50S ribosomal protein L24; TIGRFAM: ribosomal protein L24; PFAM: KOW motif; TIGRFAM: ribosomal protein L24, bacterial/organelle.
   
 0.906
rplB
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
   
 0.900
ADW19364.1
COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR004506; KEGG: dak:DaAHT2_1911 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; SPTR: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase.
     
  0.900
rplN
LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.
   
 0.899
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
  0.894
rplC
LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
  
 0.889
ADW16979.1
COGs: COG1841 Ribosomal protein L30/L7E; InterPro IPR000517: IPR005996; KEGG: dps:DP1143 50S ribosomal protein L30; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein L30; TIGRFAM: ribosomal protein L30; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle.
    
 0.887
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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