STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16849.1Protein of unknown function DUF28; COGs: COG0217 conserved hypothetical protein; InterPro IPR002876; KEGG: dps:DP2908 hypothetical protein; PFAM: protein of unknown function DUF28; SPTR: UPF0082 protein DP2908; PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family. (249 aa)    
Predicted Functional Partners:
ADW16851.1
COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; InterProIPR013849: IPR000445: IPR011114: IPR000085: IPR 003583; KEGG: dak:DaAHT2_1207 Holliday junction DNA helicase RuvA; PFAM: DNA recombination protein RuvA domain I; helix-hairpin-helix motif; RuvA domain protein; SPTR: Holliday junction DNA helicase RuvA; TIGRFAM: Holliday junction DNA helicase RuvA; manually curated; PFAM: RuvA, C-terminal domain; RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit.
   
 0.899
aspS
aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
 
  
 0.841
ADW16850.1
Crossover junction endodeoxyribonuclease RuvC; COGs: COG0817 Holliday junction resolvasome endonuclease subunit; InterPro IPR002176: IPR020563; KEGG: lpn:lpg1287 Holliday junction resolvase; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease ruvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC.
 
  
 0.832
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
   
 0.700
ADW16848.1
COGs: COG0293 23S rRNA methylase; InterPro IPR002877: IPR016448; KEGG: dps:DP2909 ribosomal RNA methyltransferase (FtsJ); PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; SPTR: Ribosomal RNA large subunit methyltransferase E; PFAM: FtsJ-like methyltransferase; TIGRFAM: cell division protein FtsJ.
  
    0.697
ADW18165.1
COGs: COG0333 Ribosomal protein L32; InterPro IPR002677; KEGG: dak:DaAHT2_1292 ribosomal protein L32; PFAM: ribosomal L32p protein; SPTR: 50S ribosomal protein L32; TIGRFAM: ribosomal protein L32; manually curated; PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32.
  
  
 0.686
ADW18377.1
Surface presentation of antigens (SPOA) protein; COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689: IPR001543; KEGG: drt:Dret_0581 flagellar motor switch protein FliM; PFAM: surface presentation of antigens (SPOA) protein; flagellar motor switch protein FliM; SPTR: Flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM.
   
   0.678
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.671
ADW16500.1
COGs: COG0143 Methionyl-tRNA synthetase; InterProIPR002547: IPR014758: IPR002304: IPR004495: IPR 015413; KEGG: dps:DP0786 methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); t-RNA-binding domain-containing protein; SPTR: Probable methionyl-tRNA synthetase; TIGRFAM: methionyl-tRNA synthetase; methionyl-tRNA synthetase, beta subunit; PFAM: Anticodon-binding domain; tRNA synthetases class I (M); Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase.
  
   0.666
ADW16846.1
Thiamine biosynthesis protein; COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR020536; KEGG: dps:DP2965 hypothetical protein; PFAM: Thiamine biosynthesis protein-like; SPTR: Thiamine biosynthesis protein; PFAM: Thiamine biosynthesis protein (ThiI).
     
 0.666
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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