Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADW16853.1Protein of unknown function DUF323; COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: dat:HRM2_08290 hypothetical protein; PFAM: protein of unknown function DUF323; SPTR: Putative uncharacterized protein; PFAM: Formylglycine-generating sulfatase enzyme. (535 aa)    
Predicted Functional Partners:
ADW16859.1
Protein of unknown function DUF214; COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: dat:HRM2_08300 ABC-type transporter, permease protein; PFAM: protein of unknown function DUF214; SPTR: ABC-type transporter, permease protein; PFAM: Predicted permease.
 
    0.901
ADW16857.1
Serine/threonine protein kinase PpkA; InterPro IPR002035; KEGG: dat:HRM2_08320 predicted serine/threonine protein kinase PpkA; SPTR: Predicted serine/threonine protein kinase PpkA.
 
     0.862
ADW16858.1
ABC transporter related protein; COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439: IPR017871: IPR003593; KEGG: dat:HRM2_08310 ABC-type transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ABC-type transporter, ATP-binding protein; PFAM: ABC transporter.
 
    0.663
ADW16854.1
KEGG: dat:HRM2_08270 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.644
ADW16855.1
KEGG: dat:HRM2_08260 serine/threonine-protein kinase MRCK alpha (CDC42-binding protein kinase alpha); SPTR: Serine/threonine-protein kinase MRCK alpha (CDC42-binding protein kinase alpha).
       0.618
ADW16758.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR013217; KEGG: dat:HRM2_20450 two component protein (cAMP receptor domain/SAM dependent regulatory domain); PFAM: cyclic nucleotide-binding; Methyltransferase type 12; SMART: cyclic nucleotide-binding; SPTR: Two component protein (CAMP receptor domain/SAM dependent regulatory domain); PFAM: Putative lysophospholipase; Cyclic nucleotide-binding domain.
  
     0.473
ADW17332.1
HRDC domain protein; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR002121; KEGG: dat:HRM2_02150 helicase-family protein; PFAM: HRDC domain protein; SMART: HRDC domain protein; SPTR: Helicase-family protein; PFAM: PIF1 helicase; HRDC domain.
 
     0.455
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.447
ADW17152.1
Abortive infection protein; InterPro IPR003675; KEGG: dat:HRM2_19830 hypothetical protein; PFAM: Abortive infection protein; SPTR: Putative uncharacterized protein; PFAM: CAAX amino terminal protease family; TIGRFAM: CAAX prenyl protease-related protein.
  
    0.424
ADW18145.1
Dihem cytochrome c; InterPro IPR018588; KEGG: dol:Dole_3094 putative lipoprotein; PFAM: Dihaem cytochrome c; SPTR: Putative di-heme cytochrome; manually curated; PFAM: Dihaem cytochrome c.
  
     0.403
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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