Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ADW16863.1S-adenosyl-methyltransferase MraW; COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; InterPro IPR002903; KEGG: dps:DP2904 hypothetical protein; PFAM: methyltransferase; SPTR: Ribosomal RNA small subunit methyltransferase H; TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: MraW methylase family; TIGRFAM: S-adenosyl-methyltransferase MraW. (306 aa)    
Predicted Functional Partners:
ADW16862.1
MraZ protein; COGs: COG2001 conserved hypothetical protein; InterPro IPR020603: IPR003444; KEGG: dak:DaAHT2_1489 MraZ protein; PFAM: MraZ domain; SPTR: Putative uncharacterized protein; TIGRFAM: MraZ protein; PFAM: MraZ protein; TIGRFAM: mraZ protein.
  
 0.989
ADW16866.1
UDP-N-acetylmuramyl-tripeptide synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterProIPR000713: IPR013221: IPR004101: IPR005761: IPR 005863; KEGG: dps:DP2901 putative bifunctional UDP-N-acetylmuramoylalanyl-D-glutamate--2,6- diaminopimelate ligase/UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimel [...]
  
 0.948
ADW16865.1
COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460: IPR005543; KEGG: dak:DaAHT2_1486 penicillin-binding protein dimerization domain protein; PFAM: Penicillin-binding protein dimerisation domain; penicillin-binding protein transpeptidase; SPTR: Penicillin-binding protein dimerization domain protein; PFAM: Penicillin-binding Protein dimerisation domain.
 
  
 0.942
ADW16868.1
COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR013221: IPR004101: IPR005762; KEGG: dak:DaAHT2_1482 UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramoylalanine/D-glutamate ligase; TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; manually curated; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase.
 
  
 0.885
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
  
  
 0.837
ADW17119.1
COGs: COG0101 Pseudouridylate synthase; InterPro IPR001406: IPR020097; KEGG: dak:DaAHT2_0355 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; SPTR: tRNA pseudouridine synthase A; TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I.
  
 
 0.832
ADW17277.1
Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: dak:DaAHT2_0193 rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.
  
   0.807
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
 
 0.798
rpsI
COGs: COG0103 Ribosomal protein S9; InterPro IPR000754: IPR020574; KEGG: dps:DP1326 30S ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family.
   
 
 0.787
ADW17456.1
Pyridoxine 5'-phosphate synthase; COGs: COG0854 Pyridoxal phosphate biosynthesis protein; InterPro IPR002036: IPR004569: IPR020549; KEGG: dps:DP1605 pyridoxal phosphate biosynthetic protein; PFAM: Pyridoxal phosphate biosynthetic protein PdxJ; protein of unknown function UPF0054; PRIAM: Pyridoxine 5'-phosphate synthase; SPTR: Probable pyridoxal phosphate biosynthetic protein; TIGRFAM: pyridoxal phosphate biosynthetic protein PdxJ; PFAM: Pyridoxal phosphate biosynthesis protein PdxJ; Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family; pyridoxine 5'-phos [...]
  
 
 
 0.785
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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