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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
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ADW16886.1Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: dak:DaAHT2_2504 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: Transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family. (196 aa)    
Predicted Functional Partners:
ADW16885.1
COGs: COG0659 Sulfate permease and related transporter (MFS superfamily); InterPro IPR011547: IPR002645: IPR001902; KEGG: dps:DP0849 high affinity sulfate transporter (SulP); PFAM: sulphate transporter; Sulfate transporter/antisigma-factor antagonist STAS; SPTR: Probable high affinity sulfate transporter (SulP); TIGRFAM: sulfate transporter; PFAM: Sulfate transporter family; STAS domain; TIGRFAM: anti-anti-sigma factor; high affinity sulphate transporter 1.
       0.710
ADW18985.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dol:Dole_2335 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain.
 
     0.610
ADW18984.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR005467: IPR003661: IPR003594: IPR004358; KEGG: dol:Dole_2334 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
 
   0.584
ADW18982.1
KEGG: dol:Dole_2332 histidine kinase A domain-containing protein; SPTR: Histidine kinase A domain-containing protein.
 
     0.532
ADW18619.1
COGs: COG0193 Peptidyl-tRNA hydrolase; InterPro IPR001328: IPR018171; KEGG: bha:BH0068 peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase.
   
    0.435
ADW16887.1
Radical SAM domain protein; COGs: COG1032 Fe-S oxidoreductase; InterPro IPR013704: IPR020612: IPR006638; KEGG: dev:DhcVS_1417 Fe-S oxidoreductase, radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Fe-S oxidoreductase, radical SAM domain protein; PFAM: Radical SAM superfamily; Radical SAM N-terminal.
       0.427
ADW16888.1
HI0933 family protein; COGs: COG2081 flavoprotein; InterPro IPR004792: IPR013027; KEGG: pca:Pcar_2050 hypothetical protein; PFAM: HI0933 family protein; SPTR: Putative uncharacterized protein; PFAM: HI0933-like protein; TIGRFAM: flavoprotein, HI0933 family.
       0.427
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
    
 
 0.417
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
    
 
 0.416
ADW17360.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 001610: IPR003018: IPR003661: IPR003594: IPR013767: IPR013656:I PR013655; KEGG: ppd:Ppro_3572 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS doma [...]
    
 
 0.402
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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