Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW16914.1COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR014730: IPR014731: IPR001308: IPR018206; KEGG: geo:Geob_0096 electron transfer flavoprotein alpha subunit; PFAM: Electron transfer flavoprotein alpha subunit; Electron transfer flavoprotein alpha/beta-subunit; SPTR: Electron transfer flavoprotein alpha subunit; PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain. (305 aa)    
Predicted Functional Partners:
ADW16913.1
COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014730: IPR012255; KEGG: ddf:DEFDS_1832 electron transfer flavoprotein subunit beta; PFAM: Electron transfer flavoprotein alpha/beta-subunit; SPTR: Electron transfer flavoprotein, beta subunit; PFAM: Electron transfer flavoprotein domain.
 0.999
ADW18161.1
COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014730: IPR012255; KEGG: dak:DaAHT2_1288 electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein alpha/beta-subunit; SPTR: Electron transfer flavoprotein alpha/beta-subunit; PFAM: Electron transfer flavoprotein domain.
 0.998
ADW16911.1
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090: IPR006089; KEGG: chy:CHY_1350 butyryl-CoA dehydrogenase; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase domain protein; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
 
 0.995
ADW18162.1
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006089: IPR006092: IPR006091: IPR006090; KEGG: dak:DaAHT2_1289 acyl-CoA dehydrogenase domain protein; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase domain protein; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
 
 0.990
ADW17871.1
COGs: COG1960 Acyl-CoA dehydrogenase; InterPro IPR006092: IPR006091: IPR006090: IPR006089; KEGG: gme:Gmet_1710 acyl-CoA dehydrogenase-like; PFAM: acyl-CoA dehydrogenase domain-containing protein; SPTR: Acyl-CoA dehydrogenase-like; PFAM: Acyl-CoA dehydrogenase, C-terminal domain; Acyl-CoA dehydrogenase, middle domain; Acyl-CoA dehydrogenase, N-terminal domain.
 
 0.989
ADW16912.1
COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017: IPR017900: IPR017896; KEGG: geo:Geob_0246 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain.
 
  
 0.895
ADW19128.1
COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027: IPR004099: IPR000815: IPR012999: IPR 006258; KEGG: alv:Alvin_0803 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase.
  
 
 0.886
sucD
succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
   
  
 0.742
ADW17654.1
Transketolase central region; COGs: COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit; InterPro IPR005475: IPR005476: IPR017871; KEGG: gur:Gura_1610 transketolase, central region; PFAM: Transketolase central region; Transketolase domain-containing protein; SPTR: Transketolase, central region; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
   
 
 0.735
ADW16228.1
Fumarase; COGs: COG0114 Fumarase; InterProIPR020557: IPR000362: IPR003031: IPR005677: IPR 018951; KEGG: dap:Dacet_2357 fumarate hydratase, class II; PFAM: fumarate lyase; Fumarase C-like; SPTR: Fumarate hydratase, class II; TIGRFAM: fumarate hydratase, class II; PFAM: Lyase; Fumarase C C-terminus; TIGRFAM: fumarate hydratase, class II.
   
  
 0.732
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (12%) [HD]