STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW16925.1Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase. (319 aa)    
Predicted Functional Partners:
ADW16818.1
COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR006076: IPR002937: IPR004572; KEGG: dps:DP0277 protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; PRIAM: Protoporphyrinogen oxidase; SPTR: Related to protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; FAD dependent oxidoreductase; TIGRFAM: protoporphyrinogen oxidase.
 
 
 0.996
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.976
ADW19242.1
Protoporphyrin IX magnesium-chelatase; COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR000523: IPR002035: IPR003593; KEGG: ppd:Ppro_1261 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; von Willebrand factor type A; PRIAM: Magnesium chelatase; SMART: von Willebrand factor type A; AAA ATPase; SPTR: Protoporphyrin IX magnesium-chelatase; PFAM: Magnesium chelatase, subunit ChlI; von Willebrand factor type A domain; TIGRFAM: cobaltochelatase subunit.
  
 
 0.941
ADW18086.1
Ferritin Dps family protein; COGs: COG2193 Bacterioferritin (cytochrome b1); InterPro IPR002024: IPR009040: IPR008331; KEGG: dap:Dacet_2337 ferritin Dps family protein; PFAM: Ferritin Dps family protein; SPTR: Ferritin Dps family protein; PFAM: Ferritin-like domain; TIGRFAM: bacterioferritin.
     
 0.927
ADW19241.1
Protoporphyrin IX magnesium-chelatase; COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR000523: IPR003593; KEGG: ppd:Ppro_1262 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; PRIAM: Magnesium chelatase; SMART: AAA ATPase; SPTR: Protoporphyrin IX magnesium-chelatase; PFAM: Magnesium chelatase, subunit ChlI.
   
 
 0.917
ADW17026.1
Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197: IPR017200: IPR006638; KEGG: dak:DaAHT2_1941 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
  
 
 0.907
nifU
Fe-S cluster assembly protein NifU; May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins.
     
 0.816
ADW18711.1
Hydroxymethylbilane synthase; COGs: COG0181 Porphobilinogen deaminase; InterPro IPR000860; KEGG: dak:DaAHT2_0535 porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; SPTR: Porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase.
 
  
 0.707
cobA
COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366: IPR003043: IPR000878: IPR003754; KEGG: dps:DP1734 uroporphyrinogen III synthase/methyltransferase (HemD+CobA); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Probable uroporphyrinogen III synthase/methyltransferase (HemD+CobA); TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase.
  
  
 0.690
ADW17958.1
COGs: COG0151 Phosphoribosylamine-glycine ligase; InterProIPR000115: IPR000031: IPR020562: IPR020561: IPR 020560: IPR011761: IPR020559; KEGG: dps:DP2188 phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PRIAM: Phosphoribosylamine--glycine ligase., Phosphoribosylaminoimidazole carboxylase; SPTR: Probable phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/ [...]
     
 0.562
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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