STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ribBAGTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (414 aa)    
Predicted Functional Partners:
ADW16940.1
COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: dak:DaAHT2_1278 riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Lumazine-binding protein; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit.
 
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.999
ADW18154.1
COGs: COG0117 Pyrimidine deaminase; InterProIPR016192: IPR004794: IPR011549: IPR002125: IPR 002734; KEGG: dak:DaAHT2_1279 riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; CMP/dCMP deaminase zinc-binding; SPTR: Riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD.
 0.999
fliG
COGs: COG1536 Flagellar motor switch protein; InterPro IPR000090; KEGG: dps:DP2657 flagellar motor switch protein (FliG); PFAM: flagellar motor switch protein FliG; SPTR: Related to flagellar motor switch protein (FliG); TIGRFAM: flagellar motor switch protein FliG; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG.
    
 
 0.933
ADW18080.1
COGs: COG0108 3 4-dihydroxy-2-butanone 4-phosphate synthase; InterPro IPR000422; KEGG: hch:HCH_01388 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; SPTR: 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase.
 
  
0.929
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
  
 0.914
ADW18117.1
GTP cyclohydrolase I; COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: dak:DaAHT2_1707 protein of unknown function DUF198; PFAM: protein of unknown function DUF198; PRIAM: GTP cyclohydrolase I; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1469.
     
 0.911
ADW18963.1
GTP cyclohydrolase I; COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: dak:DaAHT2_0489 protein of unknown function DUF198; PFAM: protein of unknown function DUF198; PRIAM: GTP cyclohydrolase I; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1469.
     
 0.911
ADW17156.1
COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterProIPR006638: IPR007197: IPR010505: IPR000385: IPR 013483; KEGG: dps:DP2172 molybdenum cofactor biosynthesis protein A (MoaA); PFAM: molybdenum cofactor synthesis domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Probable molybdenum cofactor biosynthesis protein A (MoaA); TIGRFAM: molybdenum cofactor biosynthesis protein A; PFAM: Molybdenum Cofactor Synthesis C; Radical SAM superfamily; TIGRFAM: molybdenum cofactor biosynthesis protein A, bacterial.
    
  0.902
ADW18056.1
Oxidoreductase FAD-binding domain protein; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterPro IPR001221: IPR017927: IPR008333: IPR001433; KEGG: mmi:MMAR_0128 oxidoreductase; PFAM: Oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; SPTR: Oxidoreductase; PFAM: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain.
  
  
 0.891
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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