Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW16997.1Site-2 protease; COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR008915: IPR001478: IPR004387; KEGG: dak:DaAHT2_0974 membrane-associated zinc metalloprotease; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: Membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP. (361 aa)    
Predicted Functional Partners:
ADW16994.1
COGs: COG0020 Undecaprenyl pyrophosphate synthase; InterPro IPR001441: IPR018520; KEGG: dps:DP1158 undecaprenyl pyrophosphate synthetase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: Probable undecaprenyl pyrophosphate synthetase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Putative undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase.
 
  
 0.936
ADW16996.1
COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR013512: IPR013644: IPR003821; KEGG: dps:DP1160 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase domain-containing protein; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
  
 0.928
ADW16995.1
Phosphatidate cytidylyltransferase; COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: dps:DP1159 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family.
  
  
 0.917
ADW16752.1
COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR016474: IPR010827: IPR000184; KEGG: dps:DP0281 outer membrane protein; PFAM: surface antigen (D15); surface antigen variable number repeat-containing protein; SPTR: Related to outer membrane protein; TIGRFAM: outer membrane protein assembly complex, YaeT protein; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.
  
 0.908
ADW16998.1
Peptidase M22 glycoprotease; COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR000905: IPR017861; KEGG: dps:DP1162 glycoprotein endopeptidase; PFAM: peptidase M22 glycoprotease; SPTR: Related to glycoprotein endopeptidase; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ.
  
    0.834
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
       0.767
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
 
  
 0.754
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
  
  
 0.734
ADW19285.1
COGs: COG0681 Signal peptidase I; InterPro IPR019759: IPR000223: IPR019756: IPR019757; KEGG: dps:DP0107 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Related to signal peptidase I; TIGRFAM: signal peptidase I; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type.
 
  
 0.712
ADW18927.1
Outer membrane chaperone Skp (OmpH); COGs: COG2825 Outer membrane protein; InterPro IPR005632; KEGG: dps:DP2863 hypothetical protein; PFAM: outer membrane chaperone Skp (OmpH); SPTR: Putative uncharacterized protein; PFAM: Outer membrane protein (OmpH-like).
  
  
 0.672
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (18%) [HD]