STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17005.1rRNA (guanine-N(2)-)-methyltransferase; COGs: COG0116 N6-adenine-specific DNA methylase; InterPro IPR004114: IPR000241: IPR017244: IPR002052; KEGG: dps:DP0739 23S rRNA m(2)G2445 methyltransferase; PFAM: RNA methylase; THUMP domain-containing protein; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: Ribosomal RNA large subunit methyltransferase L; PFAM: Putative RNA methylase family UPF0020; S-adenosylmethionine-dependent methyltransferase; THUMP domain. (734 aa)    
Predicted Functional Partners:
ADW19099.1
Ribosomal large subunit pseudouridine synthase B; COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942: IPR006145: IPR018496: IPR000748; KEGG: dak:DaAHT2_2545 pseudouridine synthase; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase.
  
 
 0.882
ADW18154.1
COGs: COG0117 Pyrimidine deaminase; InterProIPR016192: IPR004794: IPR011549: IPR002125: IPR 002734; KEGG: dak:DaAHT2_1279 riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; CMP/dCMP deaminase zinc-binding; SPTR: Riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD.
     
 0.828
ADW16994.1
COGs: COG0020 Undecaprenyl pyrophosphate synthase; InterPro IPR001441: IPR018520; KEGG: dps:DP1158 undecaprenyl pyrophosphate synthetase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: Probable undecaprenyl pyrophosphate synthetase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Putative undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase.
   
    0.809
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
    0.803
ADW17004.1
NUDIX hydrolase; COGs: COG1443 Isopentenyldiphosphate isomerase; InterPro IPR000086; KEGG: ppf:Pput_0604 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: IPP isomerase type 1 family protein; PFAM: NUDIX domain.
       0.773
ADW19076.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
  
    0.771
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.759
ADW17032.1
Aminodeoxychorismate lyase; COGs: COG1559 periplasmic solute-binding protein; InterPro IPR003770; KEGG: dps:DP2920 hypothetical protein; PFAM: aminodeoxychorismate lyase; SPTR: Putative uncharacterized protein; manually curated; PFAM: YceG-like family; TIGRFAM: conserved hypothetical protein, YceG family.
  
    0.741
typA
GTP-binding protein TypA; COGs: COG1217 membrane GTPase involved in stress response; InterProIPR000795: IPR004161: IPR000640: IPR005225: IPR 006298; KEGG: dps:DP0074 GTP-binding protein TypA/BipA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain-containing protein; SPTR: Probable GTP-binding protein TypA/BipA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small G [...]
  
   0.730
ADW17115.1
Gid protein; COGs: COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation; InterPro IPR002218: IPR004417; KEGG: dps:DP1969 tRNA (uracil-5-)-methyltransferase Gid; PFAM: glucose-inhibited division protein A; PRIAM:Methylenetetrahydrofolate--tRNA-(uracil-5-)-m ethyltransferase(FADH(2)-oxidizing); SPTR:Methylenetetrahydrofolate--tRNA-(uracil-5-)-me thyltransferasetrmFO; TIGRFAM: gid protein; PFAM: Glucose inhibited division protein A; TIGRFAM: tRNA:m(5)U-54 methyltransferase.
  
    0.715
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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