Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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ADW17007.1Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789: IPR002078: IPR002197: IPR003593; KEGG: gur:Gura_2708 two component, sigma-54 specific, fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Putative two component, sigma-54 specific, transcriptional regulator, Fis family; PFAM: Response reg [...] (459 aa)    
Predicted Functional Partners:
ADW16691.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: dps:DP0442 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: Probable RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.747
ADW17006.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dal:Dalk_1498 histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Histidine kinase; PFAM: Response regulator receiver domain; His Kinase A (phosphoacceptor) domain.
  
 
 0.584
ADW16797.1
PAS sensor protein; InterPro IPR013767: IPR000014; KEGG: met:M446_4819 putative PAS/PAC sensor protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
 
  
   0.453
ADW17009.1
CheW protein; COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: dps:DP2359 purine-binding chemotaxis protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: Related to purine-binding chemotaxis protein; PFAM: CheW-like domain.
  
    0.422
ADW17015.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR013767: IPR003661: IPR003594: IPR001789: IPR 004358: IPR000014: IPR001610: IPR005467: IPR000700; KEGG: dps:DP1518 Ntr family two-component system sensory/regulatory protein; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain contain [...]
  
 
 0.406
ADW17008.1
KEGG: gsu:GSU0840 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.401
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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