| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADW16818.1 | ADW16925.1 | Despr_0642 | Despr_0750 | COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR006076: IPR002937: IPR004572; KEGG: dps:DP0277 protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; PRIAM: Protoporphyrinogen oxidase; SPTR: Related to protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; FAD dependent oxidoreductase; TIGRFAM: protoporphyrinogen oxidase. | Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase. | 0.996 |
| ADW16818.1 | ADW17136.1 | Despr_0642 | Despr_0962 | COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR006076: IPR002937: IPR004572; KEGG: dps:DP0277 protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; PRIAM: Protoporphyrinogen oxidase; SPTR: Related to protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; FAD dependent oxidoreductase; TIGRFAM: protoporphyrinogen oxidase. | Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: dps:DP2824 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.552 |
| ADW16818.1 | ADW18711.1 | Despr_0642 | Despr_2575 | COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR006076: IPR002937: IPR004572; KEGG: dps:DP0277 protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; PRIAM: Protoporphyrinogen oxidase; SPTR: Related to protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; FAD dependent oxidoreductase; TIGRFAM: protoporphyrinogen oxidase. | Hydroxymethylbilane synthase; COGs: COG0181 Porphobilinogen deaminase; InterPro IPR000860; KEGG: dak:DaAHT2_0535 porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; SPTR: Porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase. | 0.575 |
| ADW16818.1 | cobA | Despr_0642 | Despr_2576 | COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR006076: IPR002937: IPR004572; KEGG: dps:DP0277 protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; PRIAM: Protoporphyrinogen oxidase; SPTR: Related to protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; FAD dependent oxidoreductase; TIGRFAM: protoporphyrinogen oxidase. | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366: IPR003043: IPR000878: IPR003754; KEGG: dps:DP1734 uroporphyrinogen III synthase/methyltransferase (HemD+CobA); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Probable uroporphyrinogen III synthase/methyltransferase (HemD+CobA); TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.606 |
| ADW16818.1 | hemE | Despr_0642 | Despr_0851 | COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR006076: IPR002937: IPR004572; KEGG: dps:DP0277 protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; PRIAM: Protoporphyrinogen oxidase; SPTR: Related to protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; FAD dependent oxidoreductase; TIGRFAM: protoporphyrinogen oxidase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.997 |
| ADW16818.1 | hemL | Despr_0642 | Despr_2958 | COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR006076: IPR002937: IPR004572; KEGG: dps:DP0277 protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; PRIAM: Protoporphyrinogen oxidase; SPTR: Related to protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; FAD dependent oxidoreductase; TIGRFAM: protoporphyrinogen oxidase. | COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814: IPR004639; KEGG: dps:DP0812 glutamate-1-semialdehyde 2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. | 0.438 |
| ADW16923.1 | ADW16925.1 | Despr_0748 | Despr_0750 | COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...] | Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase. | 0.430 |
| ADW16923.1 | hemE | Despr_0748 | Despr_0851 | COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...] | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.612 |
| ADW16923.1 | hemL | Despr_0748 | Despr_2958 | COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...] | COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814: IPR004639; KEGG: dps:DP0812 glutamate-1-semialdehyde 2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. | 0.533 |
| ADW16925.1 | ADW16818.1 | Despr_0750 | Despr_0642 | Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase. | COGs: COG1232 Protoporphyrinogen oxidase; InterPro IPR006076: IPR002937: IPR004572; KEGG: dps:DP0277 protoporphyrinogen oxidase; PFAM: amine oxidase; FAD dependent oxidoreductase; PRIAM: Protoporphyrinogen oxidase; SPTR: Related to protoporphyrinogen oxidase; TIGRFAM: protoporphyrinogen oxidase; PFAM: Flavin containing amine oxidoreductase; FAD dependent oxidoreductase; TIGRFAM: protoporphyrinogen oxidase. | 0.996 |
| ADW16925.1 | ADW16923.1 | Despr_0750 | Despr_0748 | Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase. | COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...] | 0.430 |
| ADW16925.1 | ADW17026.1 | Despr_0750 | Despr_0852 | Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase. | Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197: IPR017200: IPR006638; KEGG: dak:DaAHT2_1941 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily. | 0.910 |
| ADW16925.1 | ADW17136.1 | Despr_0750 | Despr_0962 | Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase. | Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: dps:DP2824 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. | 0.625 |
| ADW16925.1 | ADW18711.1 | Despr_0750 | Despr_2575 | Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase. | Hydroxymethylbilane synthase; COGs: COG0181 Porphobilinogen deaminase; InterPro IPR000860; KEGG: dak:DaAHT2_0535 porphobilinogen deaminase; PFAM: Porphobilinogen deaminase; SPTR: Porphobilinogen deaminase; TIGRFAM: porphobilinogen deaminase; PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase. | 0.734 |
| ADW16925.1 | cobA | Despr_0750 | Despr_2576 | Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase. | COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR006366: IPR003043: IPR000878: IPR003754; KEGG: dps:DP1734 uroporphyrinogen III synthase/methyltransferase (HemD+CobA); PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; SPTR: Probable uroporphyrinogen III synthase/methyltransferase (HemD+CobA); TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase. | 0.657 |
| ADW16925.1 | hemE | Despr_0750 | Despr_0851 | Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.969 |
| ADW16925.1 | hemL | Despr_0750 | Despr_2958 | Ferrochelatase; COGs: COG0276 Protoheme ferro-lyase (ferrochelatase); InterPro IPR001015: IPR019772; KEGG: dps:DP1085 ferrochelatase; PFAM: ferrochelatase; SPTR: Ferrochelatase; TIGRFAM: ferrochelatase; PFAM: Ferrochelatase; TIGRFAM: ferrochelatase. | COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814: IPR004639; KEGG: dps:DP0812 glutamate-1-semialdehyde 2,1-aminomutase; PFAM: aminotransferase class-III; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase. | 0.448 |
| ADW17023.1 | ADW17024.1 | Despr_0849 | Despr_0850 | PAS fold-4 domain protein; InterPro IPR013656: IPR010916; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold-4 domain protein; SPTR: PAS fold; PFAM: PAS fold. | Metal dependent phophohydrolase; InterPro IPR006674: IPR006675; KEGG: dps:DP1279 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: Putative uncharacterized protein; TIGRFAM: metal dependent phophohydrolase; manually curated; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. | 0.671 |
| ADW17023.1 | ADW17026.1 | Despr_0849 | Despr_0852 | PAS fold-4 domain protein; InterPro IPR013656: IPR010916; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold-4 domain protein; SPTR: PAS fold; PFAM: PAS fold. | Radical SAM domain protein; COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197: IPR017200: IPR006638; KEGG: dak:DaAHT2_1941 radical SAM domain protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily. | 0.510 |
| ADW17023.1 | hemE | Despr_0849 | Despr_0851 | PAS fold-4 domain protein; InterPro IPR013656: IPR010916; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold-4 domain protein; SPTR: PAS fold; PFAM: PAS fold. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.666 |