Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW17034.1NH(3)-dependent NAD(+) synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010: IPR003694: IPR014445; KEGG: dps:DP2919 glutamine-dependent NAD(+) synthetase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Probable glutamine-dependent NAD(+) synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; Carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase. (541 aa)    
Predicted Functional Partners:
ADW17259.1
COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; InterPro IPR004820: IPR005248: IPR004821; KEGG: dak:DaAHT2_1154 nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Nicotinate (Nicotinamide) nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain.
  
 
 0.958
ADW17739.1
COGs: COG0061 sugar kinase; InterPro IPR002504; KEGG: dak:DaAHT2_1073 NAD(+) kinase; PFAM: ATP-NAD/AcoX kinase; SPTR: NAD(+) kinase; PFAM: ATP-NAD kinase.
    
 0.954
ADW18107.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: acp:A2cp1_4171 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Silent information regulator protein Sir2; PFAM: Sir2 family.
    
 0.944
ADW19327.1
Silent information regulator protein Sir2; COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: dak:DaAHT2_0111 silent information regulator protein Sir2; PFAM: Silent information regulator protein Sir2; SPTR: Silent information regulator protein Sir2; PFAM: Sir2 family.
    
 0.944
ADW17340.1
COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR007229: IPR015977: IPR006405; KEGG: gsu:GSU2289 nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; PRIAM: Nicotinate phosphoribosyltransferase; SPTR: Nicotinate phosphoribosyltransferase; TIGRFAM: nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: putative nicotinate phosphoribosyltransferase.
  
  
 0.716
ADW19076.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
  
  
 0.697
ADW17166.1
Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR002701: IPR001086: IPR008242: IPR020822: IPR 002912: IPR018528; KEGG: dps:DP2171 P-protein; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Probable P-protein; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
  
  
 0.677
ADW18967.1
Recombination protein MgsA; COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959: IPR003593; KEGG: dak:DaAHT2_0693 AAA ATPase central domain protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase central domain protein; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA).
  
    0.664
ADW19366.1
Competence/damage-inducible protein cinA; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453: IPR008136: IPR008135; KEGG: dak:DaAHT2_1904 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain.
     
 0.661
ADW18154.1
COGs: COG0117 Pyrimidine deaminase; InterProIPR016192: IPR004794: IPR011549: IPR002125: IPR 002734; KEGG: dak:DaAHT2_1279 riboflavin biosynthesis protein RibD; PFAM: bifunctional deaminase-reductase domain protein; CMP/dCMP deaminase zinc-binding; SPTR: Riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; riboflavin biosynthesis protein RibD.
     
 0.659
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.