STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17061.1DNA topoisomerase III; COGs: COG0550 Topoisomerase IA; InterProIPR006171: IPR013497: IPR000380: IPR005738: IPR 006154: IPR003601: IPR003602; KEGG: dps:DP2617 DNA topoisomerase III; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain-containing protein; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain-containing protein; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase III; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacteria and conjugative plasmid. (821 aa)    
Predicted Functional Partners:
ADW17332.1
HRDC domain protein; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR002121; KEGG: dat:HRM2_02150 helicase-family protein; PFAM: HRDC domain protein; SMART: HRDC domain protein; SPTR: Helicase-family protein; PFAM: PIF1 helicase; HRDC domain.
 
 0.992
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.938
nifJ
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR011895: IPR017896: IPR017900: IPR002880: IPR 019752: IPR019456: IPR011766; KEGG: dak:DaAHT2_0906 pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; thiamine pyrophosphate TPP-binding domain-containing protein; SPTR: Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: pyruvate ferredoxin/flavod [...]
  
   0.915
ADW19358.1
SMC domain protein; COGs: COG0419 ATPase involved in DNA repair; InterPro IPR003395; KEGG: ppd:Ppro_2570 SMC domain-containing protein; PFAM: SMC domain protein; SPTR: SMC domain protein; TIGRFAM: exonuclease SbcC.
  
 0.909
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
  
 0.908
ADW19417.1
COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: dps:DP0648 DNA polymerase III, beta chain; PFAM: DNA polymerase III beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III beta chain; SPTR: Probable DNA polymerase III, beta chain; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit.
   
 0.856
ADW19357.1
COGs: COG0420 DNA repair exonuclease; InterPro IPR004843: IPR004593; KEGG: gur:Gura_1979 nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; SPTR: Exodeoxyribonuclease I subunit D; TIGRFAM: nuclease SbcCD, D subunit; PFAM: Calcineurin-like phosphoesterase; Type 5 capsule protein repressor C terminal; TIGRFAM: exonuclease SbcD.
  
 0.855
ADW18719.1
Helicase c2; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR014001: IPR006555: IPR014013; KEGG: dps:DP1744 ATP-dependent helicase; SMART: helicase c2; DEAD-like helicase; SPTR: Helicase c2; PFAM: DEAD/DEAH box helicase.
   
 0.841
ADW17479.1
COGs: COG0017 Aspartyl/asparaginyl-tRNA synthetase; InterProIPR004522: IPR006195: IPR004365: IPR004364: IPR 002312; KEGG: dps:DP1331 asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Asparaginyl-tRNA synthetase; TIGRFAM: asparaginyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase.
  
 
 0.828
ADW19022.1
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: cja:CJA_3147 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
  
  
 0.818
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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