Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17066.1Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dak:DaAHT2_0644 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family. (442 aa)    
Predicted Functional Partners:
ADW17065.1
Inosine guanosine and xanthosine phosphorylase family; COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845: IPR011268; KEGG: dak:DaAHT2_0643 purine nucleoside phosphorylase I, inosine and guanosine-specific; PFAM: purine or other phosphorylase family 1; SPTR: Inosine guanosine and xanthosine phosphorylase:Purine nucleoside phosphorylase I, inosine and guanosine-specific; TIGRFAM: inosine guanosine and xanthosine phosphorylase family; PFAM: Phosphorylase superfamily; TIGRFAM: inosine guanosine and xanthosine phosphorylase family.
 
 0.965
ADW16495.1
Amidohydrolase; COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dal:Dalk_2439 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
  
  
 
0.914
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 
  0.909
ADW16217.1
Hypothetical protein; COGs: COG0421 Spermidine synthase; KEGG: mca:MCA1034 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Spermine/spermidine synthase.
   
  0.906
ADW18905.1
Protein of unknown function DUF152; COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: dak:DaAHT2_2303 protein of unknown function DUF152; PFAM: protein of unknown function DUF152; SPTR: Putative uncharacterized protein; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family.
     
  0.900
ADW17064.1
COGs: COG0498 Threonine synthase; InterPro IPR001926: IPR004450: IPR000634; KEGG: gme:Gmet_1631 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: L-threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase.
     
 0.760
ADW17067.1
Twin-arginine translocation protein, TatA/E family subunit; InterPro IPR003369: IPR006312: IPR003998; KEGG: dps:DP2620 sec-independent protein translocase protein TatE; PFAM: sec-independent translocation protein mttA/Hcf106; SPTR: Related to Sec-independent protein translocase protein TatE; TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family.
       0.575
ADW19295.1
Xanthine dehydrogenase, molybdenum binding subunit apoprotein; COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674: IPR008274; KEGG: ppd:Ppro_1519 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: Xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; Aldehyde oxidase and xanthine dehydrogenase, a/b hammer [...]
  
 
 0.566
ADW19076.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
  
  
 0.531
ADW17062.1
COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: dps:DP2618 hypothetical protein; PFAM: Iojap-related protein; SPTR: Putative uncharacterized protein; TIGRFAM: iojap-like protein; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein.
       0.490
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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