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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17080.1COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); InterProIPR003594: IPR013507: IPR014790: IPR020667: IPR 014763; KEGG: dak:DaAHT2_1338 DNA mismatch repair protein MutL; PFAM: MutL dimerisation; DNA mismatch repair protein domain protein; ATP-binding region ATPase domain protein; SPTR: DNA mismatch repair protein MutL; TIGRFAM: DNA mismatch repair protein MutL; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; MutL C terminal dimerisation domain; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL. (612 aa)    
Predicted Functional Partners:
ADW18785.1
COGs: COG0249 Mismatch repair ATPase (MutS family); InterProIPR005748: IPR007696: IPR000432: IPR007695: IPR 007860: IPR007861; KEGG: dps:DP0840 DNA mismatch repair protein MutS; PFAM: MutS III domain protein; DNA mismatch repair protein MutS domain protein; MutS II domain protein; MutS IV domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein; SPTR: DNA mismatch repair protein mutS; TIGRFAM: DNA mismatch repair protein MutS; PFAM: MutS family domain IV; MutS domain II; MutS domain V; MutS domain I; MutS domain III; TIGRFAM: DNA mismatch repair p [...]
 
 0.999
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
   
 0.987
ADW19417.1
COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: dps:DP0648 DNA polymerase III, beta chain; PFAM: DNA polymerase III beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III beta chain; SPTR: Probable DNA polymerase III, beta chain; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit.
   
 0.948
ADW17332.1
HRDC domain protein; COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR002121; KEGG: dat:HRM2_02150 helicase-family protein; PFAM: HRDC domain protein; SMART: HRDC domain protein; SPTR: Helicase-family protein; PFAM: PIF1 helicase; HRDC domain.
  
 0.947
ADW17718.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212: IPR014016: IPR014017; KEGG: dps:DP2879 ATP-dependent DNA helicase UvrD; PFAM: UvrD/REP helicase; SPTR: Probable ATP-dependent DNA helicase, UvrD/REP family; PFAM: UvrD/REP helicase.
  
 
 0.909
ADW17260.1
UvrD/REP helicase; COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR014016: IPR014017: IPR004013: IPR000212; KEGG: gme:Gmet_3223 UvrD/REP helicase; PFAM: UvrD/REP helicase; PHP domain protein; SPTR: UvrD/REP helicase; PFAM: UvrD/REP helicase; TIGRFAM: conserved hypothetical protein TIGR00375.
   
 
 0.897
ADW17928.1
COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR018022: IPR002627; KEGG: dak:DaAHT2_0798 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA delta(2)-isopentenylpyrophosphate transferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: IPP transferase; TIGRFAM: tRNA isopentenyltransferase (miaA).
  
 0.797
recA
RecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.760
ADW18775.1
Exodeoxyribonuclease III Xth; COGs: COG0708 Exonuclease III; InterProIPR003265: IPR000097: IPR004808: IPR020847: IPR 020848: IPR004036: IPR003651: IPR005135; KEGG: dak:DaAHT2_1503 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; HhH-GPD family protein; iron-sulfur cluster loop; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD family protein; SPTR: Exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: Endonuclease/Exonuclease/phosphatase family; HhH-GPD superfamily base excision DNA repair protein; H [...]
  
 
 0.753
ADW18719.1
Helicase c2; COGs: COG1199 Rad3-related DNA helicase; InterPro IPR014001: IPR006555: IPR014013; KEGG: dps:DP1744 ATP-dependent helicase; SMART: helicase c2; DEAD-like helicase; SPTR: Helicase c2; PFAM: DEAD/DEAH box helicase.
   
 
 0.712
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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