Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW17086.1Hypothetical protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: eba:ebA6101 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Metallo-beta-lactamase superfamily. (323 aa)    
Predicted Functional Partners:
ADW17283.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027: IPR001763: IPR004099; KEGG: drt:Dret_2254 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SMART: Rhodanese domain protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-lik [...]
  
 0.639
ADW18699.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027: IPR004099; KEGG: dps:DP2890 NADH oxidase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Related to NADH oxidase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
  
 0.639
ADW17087.1
SNF2-related protein; COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterPro IPR000330: IPR001650: IPR014001: IPR014021; KEGG: sat:SYN_02071 swf/snf family helicase; PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Swf/snf family helicase; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain.
       0.543
ADW17422.1
Rhodanese domain protein; COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763: IPR001307; KEGG: gsu:GSU0930 sulfur transferase, putative, selenocysteine-containing; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Sulfur transferase, putative, selenocysteine-containing; PFAM: Rhodanese-like domain.
  
 
 0.534
ADW16748.1
Protein of unknown function DUF882; COGs: COG3108 conserved hypothetical protein; InterPro IPR017909: IPR006311: IPR010275; KEGG: pna:Pnap_3585 hypothetical protein; PFAM: protein of unknown function DUF882; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF882).
 
    0.518
ADW17456.1
Pyridoxine 5'-phosphate synthase; COGs: COG0854 Pyridoxal phosphate biosynthesis protein; InterPro IPR002036: IPR004569: IPR020549; KEGG: dps:DP1605 pyridoxal phosphate biosynthetic protein; PFAM: Pyridoxal phosphate biosynthetic protein PdxJ; protein of unknown function UPF0054; PRIAM: Pyridoxine 5'-phosphate synthase; SPTR: Probable pyridoxal phosphate biosynthetic protein; TIGRFAM: pyridoxal phosphate biosynthetic protein PdxJ; PFAM: Pyridoxal phosphate biosynthesis protein PdxJ; Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family; pyridoxine 5'-phos [...]
  
 
 0.475
groS
Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
    
 
 0.466
ADW17523.1
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027: IPR004099; KEGG: dol:Dole_2294 pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: Pyridine nucleotide-disulphide oxidoreductase dimerisation region; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
   
 0.459
ADW17759.1
Peptidase M15A; COGs: COG3108 conserved hypothetical protein; InterPro IPR013230; KEGG: sfu:Sfum_2869 hypothetical protein; PFAM: Peptidase M15A; SPTR: Putative uncharacterized protein; PFAM: Bacterial protein of unknown function (DUF882).
  
    0.448
ADW17088.1
Hypothetical protein; InterPro IPR007921; KEGG: dvm:DvMF_2393 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.445
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (10%) [HD]