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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene co-occurrence
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ADW17093.1RNA methyltransferase, TrmA family; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280: IPR001566: IPR002792; KEGG: dak:DaAHT2_0532 RNA methyltransferase, TrmA family; PFAM: (Uracil-5)-methyltransferase; SPTR: RNA methyltransferase, TrmA family; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA. (432 aa)    
Predicted Functional Partners:
ADW17118.1
Maf protein; COGs: COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; InterPro IPR003697; KEGG: dps:DP1711 septum formation protein Maf; PFAM: Maf family protein; SPTR: Maf-like protein DP1711; TIGRFAM: maf protein; PFAM: Maf-like protein; TIGRFAM: MAF protein.
      0.861
ADW17990.1
Methyltransferase type 11; InterPro IPR013216: IPR017031; KEGG: gme:Gmet_2793 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Putative uncharacterized protein; PFAM: Methyltransferase domain.
   
  
 0.748
ADW17001.1
(p)ppGpp synthetase I, SpoT/RelA; COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR006674: IPR007685: IPR004095: IPR004811: IPR 000408; KEGG: dps:DP1165 GTP pyrophosphokinase; PFAM: RelA/SpoT domain protein; metal-dependent phosphohydrolase HD sub domain; TGS domain-containing protein; PRIAM: GTP diphosphokinase; SPTR: Probable GTP pyrophosphokinase; TIGRFAM: RelA/SpoT family protein; PFAM: TGS domain; Region found in RelA / SpoT proteins; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family.
   
 0.678
ADW17092.1
COGs: COG1190 Lysyl-tRNA synthetase (class II); InterProIPR004365: IPR004364: IPR002313: IPR018149: IPR 006195; KEGG: dps:DP1629 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial.
 
  
 0.671
ADW19051.1
COGs: COG0130 Pseudouridine synthase; InterPro IPR002501: IPR014780; KEGG: dps:DP2610 tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; SPTR: tRNA pseudouridine synthase B; TIGRFAM: tRNA pseudouridine synthase B; PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase.
  
  
 0.644
ADW17005.1
rRNA (guanine-N(2)-)-methyltransferase; COGs: COG0116 N6-adenine-specific DNA methylase; InterPro IPR004114: IPR000241: IPR017244: IPR002052; KEGG: dps:DP0739 23S rRNA m(2)G2445 methyltransferase; PFAM: RNA methylase; THUMP domain-containing protein; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: Ribosomal RNA large subunit methyltransferase L; PFAM: Putative RNA methylase family UPF0020; S-adenosylmethionine-dependent methyltransferase; THUMP domain.
  
  
 0.611
ADW18093.1
COGs: COG0787 Alanine racemase; InterPro IPR000821: IPR020622: IPR001608: IPR011079; KEGG: dak:DaAHT2_1666 alanine racemase; PFAM: alanine racemase domain protein; PRIAM: Alanine racemase; SPTR: Alanine racemase; TIGRFAM: alanine racemase; PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase.
 
     0.609
ADW18922.1
RNA methyltransferase, TrmH family, group 3; COGs: COG0566 rRNA methylase; InterPro IPR013123: IPR001537: IPR004441; KEGG: dps:DP2859 tRNA/rRNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: Related to tRNA/rRNA methyltransferase; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3.
 
  
 0.555
ADW16774.1
Sun protein; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR004573: IPR006027: IPR001678: IPR018314; KEGG: dak:DaAHT2_2304 sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; SPTR: Fmu, rRNA SAM-dependent methyltransferase; TIGRFAM: sun protein; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB.
 
  
 0.554
ADW17094.1
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789: IPR002078: IPR002197: IPR020441: IPR 003593; KEGG: dak:DaAHT2_0539 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response [...]
       0.548
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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