STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17094.1Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789: IPR002078: IPR002197: IPR020441: IPR 003593; KEGG: dak:DaAHT2_0539 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response [...] (450 aa)    
Predicted Functional Partners:
ADW17765.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014: IPR003661: IPR003594: IPR013767: IPR 004358: IPR005467; KEGG: dak:DaAHT2_0611 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Signal transduction histidine kinase, nitrogen specific, NtrB; TIGRFAM: PAS sensor protein; PFAM: Histidin [...]
 
  0.954
ADW16876.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterPro IPR003661: IPR003594: IPR004358: IPR005467; KEGG: dak:DaAHT2_1474 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: ATP-binding region, ATPase-like:Histidine kinase A-like; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  0.931
ADW18989.1
Sigma 54 interacting domain protein; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR002078: IPR003660: IPR003593; KEGG: dvu:DVU0151 HAMP domain/sigma-54 interaction domain-containing protein; PFAM: sigma-54 factor interaction domain-containing protein; histidine kinase HAMP region domain protein; SMART: AAA ATPase; SPTR: HAMP domain/sigma-54 interaction domain protein; PFAM: Sigma-54 interaction domain.
  
  
 
0.921
ADW17207.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR005467: IPR003661: IPR003594; KEGG: sat:SYN_01094 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
  
 
  0.920
ADW16798.1
PAS modulated sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR001789: IPR013656: IPR002078: IPR002197: IPR 020441: IPR000014: IPR003593; KEGG: gsu:GSU2506 sensory box protein/sigma-54 dependent DNA-binding response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; PAS fold-4 domain protein; helix-turn-helix Fis-type; SMART: response regulator receiver; PAS domain containing protein; AAA ATPase; SPTR: Sensory box protein/si [...]
  
 
 
0.917
ADW16691.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: dps:DP0442 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: Probable RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.749
ADW16797.1
PAS sensor protein; InterPro IPR013767: IPR000014; KEGG: met:M446_4819 putative PAS/PAC sensor protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
 
  
   0.698
ADW17093.1
RNA methyltransferase, TrmA family; COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280: IPR001566: IPR002792; KEGG: dak:DaAHT2_0532 RNA methyltransferase, TrmA family; PFAM: (Uracil-5)-methyltransferase; SPTR: RNA methyltransferase, TrmA family; TIGRFAM: RNA methyltransferase, TrmA family; PFAM: tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA.
       0.548
ADW17095.1
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterProIPR000700: IPR001633: IPR000160: IPR000014: IPR 001610: IPR013655: IPR013656; KEGG: sfr:Sfri_0415 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; EAL domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; EAL domain protein; SPTR: Diguanylate cyclase/pho [...]
   
   0.546
ADW18175.1
PAS sensor protein; InterProIPR000014: IPR000700: IPR003018: IPR013656: IPR 003661: IPR001610; KEGG: dat:HRM2_42110 GGDEF domain family protein; PFAM: GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: GAF domain protein; PAC repeat-containing protein; histidine kinase A domain protein; SPTR: GGDEF domain family protein; TIGRFAM: PAS sensor protein; PFAM: GAF domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box.
  
 
 0.499
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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