Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW17108.1InterPro IPR019734: IPR013026: IPR001440; KEGG: cyp:PCC8801_1300 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. (711 aa)    
Predicted Functional Partners:
ADW18473.1
Tetratricopeptide TPR_1 repeat-containing protein; InterPro IPR019734: IPR013026: IPR001440; KEGG: dak:DaAHT2_0216 tetratricopeptide TPR_2 repeat protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Tetratricopeptide TPR_2 repeat protein; manually curated; PFAM: Tetratricopeptide repeat.
 
 
 0.787
ADW17741.1
Methyltransferase type 12; COGs: COG4976 methyltransferase (contains TPR repeat); InterProIPR019734: IPR011716: IPR001440: IPR013217: IPR 013026; KEGG: dps:DP2541 hypothetical protein; PFAM: Methyltransferase type 12; Tetratricopeptide TPR_1 repeat-containing protein; Tetratricopeptide TPR_3 repeat-containing protein; SPTR: Putative uncharacterized protein; PFAM: Methyltransferase domain; Tetratricopeptide repeat.
 
   
 0.773
ADW17375.1
InterPro IPR019734: IPR013026: IPR001440; KEGG: cpc:Cpar_1378 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat.
 
     0.750
ADW18669.1
Tetratricopeptide TPR_1 repeat-containing protein; COGs: COG4235 Cytochrome c biogenesis factor; InterPro IPR019734: IPR013026: IPR001440; KEGG: dak:DaAHT2_0817 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: TPR repeat; PFAM: Tetratricopeptide repeat.
 
 
   0.731
ADW16923.1
COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR020046: IPR020047: IPR002562: IPR001098: IPR 002298: IPR018320: IPR019760: IPR002421: IPR008918; KEGG: dak:DaAHT2_1946 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase A; TIGRFAM: DNA polymerase I; PFAM: 5'-3' exonuclea [...]
  
    0.683
ADW18308.1
Tetratricopeptide TPR_1 repeat-containing protein; COGs: COG0457 FOG: TPR repeat; InterPro IPR019734: IPR013026: IPR001440; KEGG: azl:AZL_f01560 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: TPR repeat-containing protein; PFAM: ChAPs (Chs5p-Arf1p-binding proteins); Tetratricopeptide repeat.
 
 
 0.650
ADW16609.1
FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterProIPR000253: IPR003439: IPR013525: IPR017871: IPR 003593; KEGG: cag:Cagg_0751 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; PFAM: ABC transporter related; Forkhead-associated protein; ABC-2 type transporter; SMART: Forkhead-associated protein; AAA ATPase; SPTR: FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; PFAM: ABC transporter; FHA domain; ABC-2 type transporter.
 
  
 0.634
ADW17107.1
Von Willebrand factor type A; InterPro IPR002035: IPR011449: IPR013424; KEGG: rde:RD1_B0031 von Willebrand factor type A domain-containing protein; PFAM: von Willebrand factor type A; protein of unknown function DUF1555; SMART: von Willebrand factor type A; SPTR: von Willebrand factor type A; PFAM: PEP-CTERM motif; von Willebrand factor type A domain; TIGRFAM: PEP-CTERM putative exosortase interaction domain.
     
 0.618
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
 
   
 0.583
ADW16602.1
Sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR000253: IPR002078: IPR020441: IPR003018: IPR 002197: IPR003593; KEGG: psl:Psta_3595 transcriptional regulator, NifA subfamily, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; Forkhead-associated protein; GAF domain protein; helix-turn-helix Fis-type; SMART: Forkhead-associated protein; GAF domain protein; AAA ATPase; SPTR: Transcriptional regulator, NifA subfamily, Fis Family; PFAM: GAF domain; Bacter [...]
  
  
 0.577
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (24%) [HD]