STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17109.1D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139: IPR006140: IPR000169; KEGG: dps:DP1709 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: Related to D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. (400 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
 0.999
ADW17063.1
COGs: COG0696 Phosphoglyceromutase; InterPro IPR011258: IPR006124: IPR005995; KEGG: dak:DaAHT2_0641 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; PFAM: BPG-independent PGAM domain protein; metalloenzyme domain protein; PRIAM: Phosphoglycerate mutase; SPTR: Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; TIGRFAM: phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; PFAM: Metalloenzyme superfamily; BPG-independent PGAM N-terminus (iPGM_N); TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase.
    
 0.914
ADW18706.1
COGs: COG3635 phosphoglycerate mutase AP superfamily; InterPro IPR004456: IPR013371: IPR019304: IPR006124; KEGG: dak:DaAHT2_0884 proposed homoserine kinase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein; PRIAM: Phosphoglycerate mutase; SPTR: Cofactor-independent phosphoglycerate mutase, archaeal; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: Metalloenzyme superfamily; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mu [...]
    
 0.909
ADW16545.1
COGs: COG2046 ATP sulfurylase (sulfate adenylyltransferase); InterPro IPR002891: IPR002650; KEGG: drt:Dret_2034 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; PFAM: ATP-sulfurylase; adenylylsulfate kinase; PRIAM: Sulfate adenylyltransferase., Adenylyl-sulfate kinase; SPTR: Adenylylsulfate kinase; TIGRFAM: adenylylsulfate kinase; PFAM: ATP-sulfurylase; Adenylylsulphate kinase; TIGRFAM: adenylylsulfate kinase (apsK); ATP sulphurylase.
   
  
 0.865
ADW16977.1
COGs: COG0097 Ribosomal protein L6P/L9E; InterPro IPR020040: IPR019906: IPR000702: IPR002358; KEGG: dak:DaAHT2_1437 ribosomal protein L6; PFAM: Ribosomal protein L6, alpha-beta domain; SPTR: Ribosomal protein L6; TIGRFAM: ribosomal protein L6; PFAM: Ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type.
    
   0.851
rplB
LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
   0.822
ADW17064.1
COGs: COG0498 Threonine synthase; InterPro IPR001926: IPR004450: IPR000634; KEGG: gme:Gmet_1631 threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; PRIAM: Threonine synthase; SPTR: L-threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase.
  
  
 0.821
ADW19079.1
Hypothetical protein; InterPro IPR000608: IPR019734; KEGG: dps:DP0803 hypothetical protein; SPTR: Putative uncharacterized protein.
    
 0.800
rplQ
COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: dak:DaAHT2_1424 ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; manually curated; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17.
   
   0.799
rplP
LSU ribosomal protein L16P; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
   
   0.784
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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