Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17119.1COGs: COG0101 Pseudouridylate synthase; InterPro IPR001406: IPR020097; KEGG: dak:DaAHT2_0355 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; SPTR: tRNA pseudouridine synthase A; TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I. (274 aa)    
Predicted Functional Partners:
rplQ
COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: dak:DaAHT2_1424 ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: Ribosomal protein L17; TIGRFAM: ribosomal protein L17; manually curated; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17.
 
  
 0.926
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.885
ADW17277.1
Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: dak:DaAHT2_0193 rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.
   
 
 0.837
ADW16863.1
S-adenosyl-methyltransferase MraW; COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; InterPro IPR002903; KEGG: dps:DP2904 hypothetical protein; PFAM: methyltransferase; SPTR: Ribosomal RNA small subunit methyltransferase H; TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: MraW methylase family; TIGRFAM: S-adenosyl-methyltransferase MraW.
  
 
 0.832
ADW19051.1
COGs: COG0130 Pseudouridine synthase; InterPro IPR002501: IPR014780; KEGG: dps:DP2610 tRNA pseudouridine synthase B; PFAM: pseudouridylate synthase TruB domain protein; SPTR: tRNA pseudouridine synthase B; TIGRFAM: tRNA pseudouridine synthase B; PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase.
  
 
 0.831
ADW17120.1
N-acetyl-gamma-glutamyl-phosphate reductase; COGs: COG0002 Acetylglutamate semialdehyde dehydrogenase; InterPro IPR000534: IPR012280: IPR000706; KEGG: dps:DP1325 N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase NAD - binding; Semialdehyde dehydrogenase dimerisation region; PRIAM: N-acetyl-gamma-glutamyl-phosphate reductase; SPTR: N-acetyl-gamma-glutamyl-phosphate reductase; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: N-acetyl-gamma-gluta [...]
       0.813
rpsI
COGs: COG0103 Ribosomal protein S9; InterPro IPR000754: IPR020574; KEGG: dps:DP1326 30S ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: Ribosomal protein S9/S16; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.796
ADW19359.1
COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439: IPR005876: IPR017871: IPR003593; KEGG: gsu:GSU1281 cobalt ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: ATPase component NikO of energizing module of nickel ECF transporter; TIGRFAM: cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter; TIGRFAM: cobalt transport protein ATP-binding subunit.
  
  
 0.784
ADW17118.1
Maf protein; COGs: COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; InterPro IPR003697; KEGG: dps:DP1711 septum formation protein Maf; PFAM: Maf family protein; SPTR: Maf-like protein DP1711; TIGRFAM: maf protein; PFAM: Maf-like protein; TIGRFAM: MAF protein.
       0.778
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.768
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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