Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17125.1PP-loop domain protein; COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR012089: IPR011063: IPR002362; KEGG: dps:DP1330 hypothetical protein; PFAM: PP-loop domain protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: PP-loop family. (253 aa)    
Predicted Functional Partners:
ADW17126.1
Protein of unknown function DUF89; COGs: COG1578 conserved hypothetical protein; InterPro IPR014444: IPR002791; KEGG: dol:Dole_1580 hypothetical protein; PFAM: protein of unknown function DUF89; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function DUF89.
       0.792
ADW17128.1
COGs: COG0515 Serine/threonine protein kinase; InterProIPR000719: IPR020635: IPR002290: IPR017442: IPR 017441: IPR008271; KEGG: dde:Dde_3468 serine/threonine protein kinase; PFAM: Serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, catalytic domain; SPTR: Serine/threonine protein kinase; PFAM: Protein kinase domain; Protein of unknown function (DUF1566).
       0.781
ADW17127.1
Metallophosphoesterase; InterPro IPR011152: IPR004843; KEGG: drt:Dret_1710 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: Metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase.
       0.773
ADW18619.1
COGs: COG0193 Peptidyl-tRNA hydrolase; InterPro IPR001328: IPR018171; KEGG: bha:BH0068 peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase.
  
  
 0.769
ADW17690.1
COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR005232; KEGG: rci:RCIA125 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: conserved hypothetical protein TIGR00268.
 
    0.730
ADW17124.1
KEGG: dps:DP1329 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.703
ADW17129.1
KEGG: dak:DaAHT2_2038 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.682
ADW17130.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR004358: IPR005467: IPR003660: IPR003594; KEGG: dba:Dbac_0214 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SPTR: Histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
     
 0.614
ADW17199.1
COGs: COG0107 Imidazoleglycerol-phosphate synthase; InterProIPR017926: IPR014640: IPR000991: IPR006062: IPR 010139: IPR004651; KEGG: dak:DaAHT2_2087 imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: histidine biosynthesis protein; glutamine amidotransferase class-I; SPTR: Imidazoleglycerol phosphate synthase, cyclase subunit; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: Glutamine amidotransferase class-I; Histidine biosynthesis protein; TIGRFAM: imidazole glycerol phosphate sy [...]
  
 
 0.581
ADW16753.1
COGs: COG1197 Transcription-repair coupling factor (superfamily II helicase); InterProIPR014021: IPR001650: IPR004576: IPR003711: IPR 011545: IPR005118: IPR014001; KEGG: dak:DaAHT2_1310 transcription-repair coupling factor; PFAM: transcription factor CarD; DEAD/DEAH box helicase domain protein; helicase domain protein; TRCF domain protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: Transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: Helicase conserved C-terminal domain; TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; TIG [...]
  
    0.570
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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