STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
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Coexpression
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[Homology]
Score
ADW17130.1COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterPro IPR004358: IPR005467: IPR003660: IPR003594; KEGG: dba:Dbac_0214 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SPTR: Histidine kinase; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. (652 aa)    
Predicted Functional Partners:
ADW16602.1
Sigma54 specific transcriptional regulator, Fis family; COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR000253: IPR002078: IPR020441: IPR003018: IPR 002197: IPR003593; KEGG: psl:Psta_3595 transcriptional regulator, NifA subfamily, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; Forkhead-associated protein; GAF domain protein; helix-turn-helix Fis-type; SMART: Forkhead-associated protein; GAF domain protein; AAA ATPase; SPTR: Transcriptional regulator, NifA subfamily, Fis Family; PFAM: GAF domain; Bacter [...]
   
 
 0.962
ADW17131.1
Response regulator receiver modulated metal dependent phosphohydrolase; COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789: IPR003607: IPR006674: IPR005829; KEGG: dba:Dbac_0215 response regulator receiver modulated metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; response regulator receiver; SMART: metal-dependent phosphohydrolase HD region; response regulator receiver; SPTR: Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: Domain of unknown function (DUF336 [...]
 
   0.950
ADW17348.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 000700: IPR008207: IPR001610: IPR003661: IPR003594: IPR013656:I PR013767; KEGG: alv:Alvin_2605 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator re [...]
 
0.934
ADW18652.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR000014: IPR001610: IPR003018: IPR 003661: IPR003594: IPR001789: IPR008207: IPR005467: IPR000700:I PR013767: IPR013655: IPR013656; KEGG: alv:Alvin_0242 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS fold domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain pro [...]
 
 
 
 0.933
ADW17360.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 001610: IPR003018: IPR003661: IPR003594: IPR013767: IPR013656:I PR013655; KEGG: ppd:Ppro_3572 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; PAS doma [...]
 
 
 
0.924
ADW17885.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014: IPR003018: IPR003661: IPR003594: IPR 001789: IPR013656: IPR013655: IPR004358: IPR005467: IPR000700; KEGG: dal:Dalk_4421 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; GAF domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; GAF domain protein; PAS domain containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: Multi-s [...]
 
 
0.920
ADW19026.1
Integral membrane sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR005467: IPR001789: IPR003660: IPR003661: IPR 003594: IPR004358; KEGG: gbm:Gbem_3181 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; response regulator receiver; SPTR: Hpt sensor hybrid histidine kinase; [...]
 
 
0.882
ADW16898.1
Adenylate/guanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR001054: IPR018297; KEGG: bja:blr2288 two-component hybrid sensor and regulator; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SPTR: Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain.
 
 
 0.849
ADW16609.1
FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; COGs: COG1131 ABC-type multidrug transport system ATPase component; InterProIPR000253: IPR003439: IPR013525: IPR017871: IPR 003593; KEGG: cag:Cagg_0751 FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; PFAM: ABC transporter related; Forkhead-associated protein; ABC-2 type transporter; SMART: Forkhead-associated protein; AAA ATPase; SPTR: FHA modulated ABC efflux pump with fused ATPase and integral membrane subunits; PFAM: ABC transporter; FHA domain; ABC-2 type transporter.
  
 
 0.840
ADW18650.1
COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR003660: IPR000014: IPR001610: IPR 003661: IPR003594: IPR001789: IPR005467: IPR000700: IPR008207:I PR013655; KEGG: dba:Dbac_2628 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold-3 domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain contai [...]
 
 0.836
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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