Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
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ADW17137.1Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR020441: IPR002078: IPR001789: IPR003593: IPR 002197; KEGG: dps:DP2823 Ntr family protein two-component system response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Related to two-component system response regulator (Ntr family); PFAM: Response regulator receiver domai [...] (454 aa)    
Predicted Functional Partners:
ADW17138.1
COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR004358: IPR005467: IPR000014: IPR003660: IPR 017232: IPR003661: IPR003594: IPR013767; KEGG: dps:DP2822 Ntr two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: R [...]
 
  0.978
ADW16691.1
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394: IPR007046: IPR007634; KEGG: dps:DP0442 RNA polymerase sigma-54 factor; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: Probable RNA polymerase sigma-54 factor; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor.
 
   
 0.699
ADW17139.1
KEGG: dak:DaAHT2_0340 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.619
ADW16797.1
PAS sensor protein; InterPro IPR013767: IPR000014; KEGG: met:M446_4819 putative PAS/PAC sensor protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold; TIGRFAM: PAS domain S-box.
 
  
   0.579
ADW17136.1
Porphobilinogen synthase; COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: dps:DP2824 delta-aminolevulinic acid dehydratase; PFAM: delta-aminolevulinic acid dehydratase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; PFAM: Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
       0.567
ADW18610.1
COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR004358: IPR000014: IPR003661: IPR003594: IPR 005467: IPR013767; KEGG: dak:DaAHT2_0959 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: PAS:ATP-binding region, ATPase-like:Histidine kinase A-like; TIGRFAM: PAS sensor protein; PFAM: [...]
  
   0.440
ADW17318.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: aav:Aave_0872 two component, sigma54 specific, fis family transcriptional regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain.
  
     0.434
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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