close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17138.1COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR004358: IPR005467: IPR000014: IPR003660: IPR 017232: IPR003661: IPR003594: IPR013767; KEGG: dps:DP2822 Ntr two-component system sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: R [...] (740 aa)    
Predicted Functional Partners:
ADW17137.1
Two component, sigma54 specific, transcriptional regulator, Fis family; COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR020441: IPR002078: IPR001789: IPR003593: IPR 002197; KEGG: dps:DP2823 Ntr family protein two-component system response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Related to two-component system response regulator (Ntr family); PFAM: Response regulator receiver domai [...]
  0.978
ADW17139.1
KEGG: dak:DaAHT2_0340 hypothetical protein; SPTR: Putative uncharacterized protein.
 
     0.831
ADW18364.1
COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: pca:Pcar_1193 flagellar hook-basal body complex protein FliE; PFAM: flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE.
  
 
 0.819
ADW18365.1
Flagellar M-ring protein FliF; COGs: COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein; InterPro IPR000067: IPR006182: IPR013556; KEGG: dps:DP2656 flagellar M-ring protein (FliF); PFAM: secretory protein YscJ/FliF family protein; Flagellar M-ring domain protein; SPTR: Flagellar M-ring protein FliF; TIGRFAM: flagellar M-ring protein FliF; PFAM: Flagellar M-ring protein C-terminal; Secretory protein of YscJ/FliF family; TIGRFAM: flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF).
  
    0.807
ADW18385.1
COGs: COG1419 Flagellar GTP-binding protein; InterPro IPR003593: IPR000897: IPR020006; KEGG: dps:DP2676 flagellar biosynthesis protein (FlhF); PFAM: GTP-binding signal recognition particle SRP54 G- domain; SMART: AAA ATPase; SPTR: Related to flagellar biosynthesis protein (FlhF); TIGRFAM: flagellar biosynthetic protein FlhF; PFAM: SRP54-type protein, GTPase domain; TIGRFAM: flagellar biosynthetic protein FlhF.
  
  
 0.801
flhA
Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
  
  
 0.627
ADW17352.1
COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358: IPR005467: IPR000014: IPR000700: IPR 003661: IPR003594: IPR013767; KEGG: dak:DaAHT2_1107 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Response regulator receiver; TIGRFAM: PAS sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90 [...]
 
 
 
0.605
ADW17242.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 003594: IPR013656; KEGG: dak:DaAHT2_2397 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protei [...]
 
 
 
0.579
ADW16668.1
COGs: COG1452 Organic solvent tolerance protein OstA; InterPro IPR007543; KEGG: dps:DP3010 organic solvent tolerance protein (OstA); PFAM: Organic solvent tolerance protein; SPTR: Related to organic solvent tolerance protein (OstA); PFAM: Organic solvent tolerance protein.
  
     0.578
ADW19463.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789: IPR001867; KEGG: dak:DaAHT2_1570 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
  
 
 
 0.507
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (18%) [HD]