Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17143.1Peptidase M23; COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR016047; KEGG: dps:DP2555 lipoprotein NlpD/LppB; PFAM: Peptidase M23; SPTR: Related to lipoprotein NlpD/LppB; PFAM: Peptidase family M23. (391 aa)    
Predicted Functional Partners:
ADW17144.1
Protein of unknown function DUF214; COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: dps:DP2554 cell division protein (FtsX); PFAM: protein of unknown function DUF214; SPTR: Related to cell division protein (FtsX); PFAM: Predicted permease.
 
 
 
 0.992
ADW17145.1
Cell division ATP-binding protein FtsE; COGs: COG2884 ATPase involved in cell division; InterPro IPR003439: IPR003593: IPR005286; KEGG: dps:DP2553 cell division ATP-binding protein (FtsE); PFAM: ABC transporter related; SMART: AAA ATPase; SPTR: Probable cell division ATP-binding protein (FtsE); TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter; TIGRFAM: cell division ATP-binding protein FtsE.
 
 
 
 0.981
ADW18786.1
Cell wall hydrolase/autolysin; COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: dak:DaAHT2_1892 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase.
 
 
 
 0.908
ADW17142.1
COGs: COG0793 Periplasmic protease; InterPro IPR001478: IPR005151: IPR004447; KEGG: dak:DaAHT2_1199 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: Carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc).
  
  
 0.725
ADW19063.1
COGs: COG1573 Uracil-DNA glycosylase; InterPro IPR005122: IPR000276; KEGG: dak:DaAHT2_0273 phage SPO1 DNA polymerase-related protein; PFAM: Uracil-DNA glycosylase superfamily; SPTR: Phage SPO1 DNA polymerase-related protein; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4.
   
   0.700
ADW17079.1
Penicillin-binding protein, 1A family; COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001264: IPR001460: IPR011816: IPR022272; KEGG: dak:DaAHT2_0246 penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family.
  
     0.677
ADW17057.1
Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264: IPR001460: IPR003029; KEGG: dps:DP1675 penicillin-binding protein 1A; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Glycosyl transferase, family 51; PFAM: Transglycosylase.
  
   
 0.666
ADW18305.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: geo:Geob_0641 TPR repeat-containing protein; PFAM: glycosyl transferase group 1; SPTR: TPR repeat-containing protein; PFAM: Glycosyl transferases group 1.
  
 
 0.588
ADW17862.1
Peptidase M48 Ste24p; COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR019734: IPR001915: IPR013026; KEGG: dps:DP2629 hypothetical protein; PFAM: peptidase M48 Ste24p; SPTR: Putative uncharacterized protein; PFAM: Peptidase family M48.
 
 
   0.556
ADW16856.1
Peptidase S41; COGs: COG0793 Periplasmic protease; InterPro IPR001478: IPR005151; KEGG: dat:HRM2_08250 CtpA1; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: Peptidase S41; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc).
  
  
 0.521
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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