STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17156.1COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterProIPR006638: IPR007197: IPR010505: IPR000385: IPR 013483; KEGG: dps:DP2172 molybdenum cofactor biosynthesis protein A (MoaA); PFAM: molybdenum cofactor synthesis domain protein; Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Probable molybdenum cofactor biosynthesis protein A (MoaA); TIGRFAM: molybdenum cofactor biosynthesis protein A; PFAM: Molybdenum Cofactor Synthesis C; Radical SAM superfamily; TIGRFAM: molybdenum cofactor biosynthesis protein A, bacterial. (348 aa)    
Predicted Functional Partners:
ADW18121.1
GTP cyclohydrolase subunit MoaC; COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: dps:DP1483 molybdenum cofactor biosynthesis protein C (MoaC); PFAM: molybdopterin cofactor biosynthesis protein MoaC; SPTR: Probable molybdenum cofactor biosynthesis protein C (MoaC); TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC.
 
 0.999
ADW18240.1
Molybdenum cofactor synthesis domain protein; COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR020817: IPR005110: IPR001453: IPR005111; KEGG: sfu:Sfum_1700 molybdenum cofactor synthesis domain-containing protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; SPTR: Molybdopterin molybdochelatase; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain.
 
 0.929
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
  0.902
ADW18117.1
GTP cyclohydrolase I; COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: dak:DaAHT2_1707 protein of unknown function DUF198; PFAM: protein of unknown function DUF198; PRIAM: GTP cyclohydrolase I; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1469.
     
  0.900
ADW18963.1
GTP cyclohydrolase I; COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: dak:DaAHT2_0489 protein of unknown function DUF198; PFAM: protein of unknown function DUF198; PRIAM: GTP cyclohydrolase I; SPTR: Putative uncharacterized protein; PFAM: Uncharacterized ACR, COG1469.
     
  0.900
ADW18463.1
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453: IPR008284: IPR020817; KEGG: dak:DaAHT2_1080 molybdenum cofactor synthesis domain protein; PFAM: molybdopterin binding domain; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
 
  
 0.891
ADW18241.1
COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR020817: IPR005110: IPR001453: IPR005111; KEGG: dol:Dole_0684 putative molybdopterin biosynthesis protein MoeA/LysR substrate binding-domain-containing protein; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; MoeA domain protein domain IV; SPTR: Molybdenum cofactor synthesis domain; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain.
 
 0.876
ADW16898.1
Adenylate/guanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR001054: IPR018297; KEGG: bja:blr2288 two-component hybrid sensor and regulator; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SPTR: Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain.
   
 0.833
ADW18239.1
thiamineS protein; InterPro IPR003749; KEGG: dps:DP2477 molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; SPTR: Similar to molybdopterin converting factor, subunit 1; PFAM: ThiS family.
  
  
 0.830
ADW18966.1
Adenylate/guanylate cyclase with GAF sensor(s); COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054: IPR003018; KEGG: dal:Dalk_4220 adenylate/guanylate cyclase with GAF sensor(s); PFAM: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase with GAF sensor(S); manually curated; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain.
  
 0.827
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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