close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17174.1Isochorismatase hydrolase; COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: ppd:Ppro_1867 isochorismatase hydrolase; PFAM: isochorismatase hydrolase; SPTR: Isochorismatase hydrolase; PFAM: Isochorismatase family. (181 aa)    
Predicted Functional Partners:
ADW17264.1
Carbohydrate kinase, YjeF related protein; COGs: COG0063 sugar kinase; InterPro IPR000631: IPR004443: IPR017953; KEGG: dak:DaAHT2_0242 carbohydrate kinase, YjeF related protein; PFAM: YjeF-family domain-containing protein; protein of unknown function UPF0031; SPTR: Carbohydrate kinase, YjeF related protein; TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; Carbohydrate kinase; TIGRFAM: yjeF N-terminal region; yjeF C-terminal region, hydroxyethylthiazole kinase-related.
  
    0.641
ADW17175.1
Excalibur domain protein; InterPro IPR002059: IPR008613; KEGG: eba:ebA2865 cold shock family protein; PFAM: Excalibur domain protein; Cold-shock protein DNA-binding; SPTR: Probable cold shock family protein; PFAM: 'Cold-shock' DNA-binding domain; Excalibur calcium-binding domain.
  
    0.524
ADW17034.1
NH(3)-dependent NAD(+) synthetase; COGs: COG0171 NAD synthase; InterPro IPR003010: IPR003694: IPR014445; KEGG: dps:DP2919 glutamine-dependent NAD(+) synthetase; PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Probable glutamine-dependent NAD(+) synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; Carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase.
  
 
 0.518
ADW19076.1
COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143: IPR004408; KEGG: tjr:TherJR_0220 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; manually curated; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region.
     
 0.475
ADW17176.1
COGs: COG2818 3-methyladenine DNA glycosylase; InterPro IPR005019: IPR004597; KEGG: dat:HRM2_24080 Tag; PFAM: methyladenine glycosylase; PRIAM: DNA-3-methyladenine glycosylase I; SPTR: DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: Methyladenine glycosylase; TIGRFAM: DNA-3-methyladenine glycosylase I.
       0.433
ADW17173.1
KEGG: dps:DP0172 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.429
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.418
ADW19420.1
COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR011128: IPR006109: IPR006168; KEGG: dps:DP0651 glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+]; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus.
  
   0.417
ADW18305.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: geo:Geob_0641 TPR repeat-containing protein; PFAM: glycosyl transferase group 1; SPTR: TPR repeat-containing protein; PFAM: Glycosyl transferases group 1.
 
  
 0.405
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: medium (48%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.