STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17177.1Pentapeptide repeat protein; COGs: COG1357 Uncharacterized low-complexity protein; InterPro IPR001646; KEGG: cch:Cag_1224 hypothetical protein; PFAM: pentapeptide repeat protein; SPTR: Uncharacterized low-complexity proteins-like; PFAM: Pentapeptide repeats (8 copies). (754 aa)    
Predicted Functional Partners:
ADW17674.1
Abortive phage infection; InterPro IPR018891; KEGG: neu:NE0489 abortive infection phage resistance protein; PFAM: Abortive phage infection; SPTR: Possible abortive infection phage resistance protein; PFAM: AIPR protein.
    
 
 0.585
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.585
ADW17672.1
DNA topoisomerase IV subunit B; COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterPro IPR003594: IPR013506: IPR001241: IPR000565; KEGG: dps:DP2280 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIA subunit B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; SPTR: Probable topoisomerase IV, subunit B; PFAM: Toprim domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus.
    
 
 0.564
ADW16578.1
Tetratricopeptide TPR_1 repeat-containing protein; InterPro IPR019734: IPR013026: IPR002151: IPR001440; KEGG: cpc:Cpar_1554 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; SPTR: Kinesin light chain isoform 1; PFAM: Tetratricopeptide repeat.
 
    0.536
ADW18305.1
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: geo:Geob_0641 TPR repeat-containing protein; PFAM: glycosyl transferase group 1; SPTR: TPR repeat-containing protein; PFAM: Glycosyl transferases group 1.
  
  
 0.483
ADW17056.1
COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258: IPR018392: IPR000189: IPR002482; KEGG: dak:DaAHT2_1690 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase catalytic; Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Lytic transglycosylase catalytic; PFAM: Transglycosylase SLT domain; LysM domain.
   
 
 0.460
ADW18894.1
Peptidoglycan-binding lysin domain protein; InterPro IPR002482: IPR018392; KEGG: nhl:Nhal_1845 ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Cell division protein FtsY; PFAM: LysM domain.
   
 
 0.443
ADW18939.1
Lytic transglycosylase catalytic; InterPro IPR008258: IPR000189; KEGG: dps:DP2874 hypothetical protein; PFAM: Lytic transglycosylase catalytic; SPTR: Putative uncharacterized protein; PFAM: Transglycosylase SLT domain.
   
 
 0.443
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.