Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW17210.1Rhodanese domain protein; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: dba:Dbac_1785 rhodanese domain protein; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein; PFAM: Rubrerythrin; Rhodanese-like domain. (272 aa)    
Predicted Functional Partners:
ADW18242.1
UBA/THIF-type NAD/FAD binding protein; COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR006140: IPR000594; KEGG: gur:Gura_1193 UBA/ThiF-type NAD/FAD binding protein; PFAM: UBA/THIF-type NAD/FAD binding protein; SPTR: UBA/THIF-type NAD/FAD binding protein; PFAM: MoeZ/MoeB domain; ThiF family.
 
  
 0.936
nifS
Cysteine desulfurase NifS; Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine.
  
 0.925
ADW18239.1
thiamineS protein; InterPro IPR003749; KEGG: dps:DP2477 molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; SPTR: Similar to molybdopterin converting factor, subunit 1; PFAM: ThiS family.
    
 0.916
ADW18043.1
COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterProIPR020845: IPR009081: IPR006163: IPR000873: IPR 002123; KEGG: ppr:PBPRB0014 acyltransferase family protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: Hypothetical acyltransferase family protein; PFAM: Phosphopantetheine attachment site; Acyltransferase; AMP-binding enzyme; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases.
  
 
 0.786
ADW17955.1
Rhodanese domain protein; COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: gsu:GSU0930 sulfur transferase, putative, selenocysteine-containing; SMART: Rhodanese domain protein; SPTR: Sulfur transferase, putative, selenocysteine-containing; PFAM: Rhodanese-like domain.
 
 
 0.719
ADW18056.1
Oxidoreductase FAD-binding domain protein; COGs: COG1018 Flavodoxin reductase (ferredoxin-NADPH reductase) family 1; InterPro IPR001221: IPR017927: IPR008333: IPR001433; KEGG: mmi:MMAR_0128 oxidoreductase; PFAM: Oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; SPTR: Oxidoreductase; PFAM: Oxidoreductase FAD-binding domain; Oxidoreductase NAD-binding domain.
  
 
 0.627
ADW18078.1
COGs: COG0225 Peptide methionine sulfoxide reductase; InterPro IPR002569: IPR002579; KEGG: tau:Tola_0999 methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; Methionine sulfoxide reductase A; PRIAM: Peptide-methionine (S)-S-oxide reductase., Peptide-methionine (R)-S-oxide reductase; SPTR: Methionine-R-sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; peptide methionine sulfoxide reductase; PFAM: SelR domain; Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase.
  
  
 0.568
ADW17209.1
Hypothetical protein.
       0.566
ADW17909.1
COGs: COG0605 Superoxide dismutase; InterPro IPR019831: IPR019832: IPR001189: IPR019833; KEGG: efa:EF0463 superoxide dismutase, Mn; PFAM: Manganese/iron superoxide dismutase-like; PRIAM: Superoxide dismutase; SPTR: Superoxide dismutase; PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain.
  
 
 0.547
ADW17277.1
Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: dak:DaAHT2_0193 rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.
 
 
 0.541
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (26%) [HD]