Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ADW17223.1COGs: COG1109 Phosphomannomutase; InterProIPR005841: IPR005844: IPR005845: IPR005846: IPR 005843: IPR016066: IPR006352; KEGG: dps:DP1641 phosphoglucomutase/phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: Phosphoglucosamine mutase; TIGRFAM: phosphoglucosamine mutase; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomanno [...] (450 aa)    
Predicted Functional Partners:
ADW18739.1
UDP-N-acetylglucosamine pyrophosphorylase; COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR000215: IPR005835: IPR001451; KEGG: dak:DaAHT2_0919 glucosamine-1-phosphate N-acetyltransferase; PFAM: Nucleotidyl transferase; transferase hexapeptide repeat containing protein; SPTR: Glucosamine-1-phosphate N-acetyltransferase; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase.
 
  
 0.948
glmS
Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 0.944
ADW17030.1
Transferase hexapeptide repeat containing protein; COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); InterPro IPR001451; KEGG: dps:DP2923 bifunctional GlmU protein; PFAM: transferase hexapeptide repeat containing protein; SPTR: Probable bifunctional GlmU protein.
 
  
 0.930
ADW17225.1
Protein of unknown function DUF147; COGs: COG1624 conserved hypothetical protein; InterPro IPR014046: IPR003390; KEGG: dps:DP1639 hypothetical protein; PFAM: protein of unknown function DUF147; SPTR: Conserved hypothetical membrane protein; PFAM: DisA bacterial checkpoint controller nucleotide-binding; TIGRFAM: conserved hypothetical protein TIGR00159.
   
 
 0.903
ADW18641.1
Protein of unknown function DUF147; COGs: COG1624 conserved hypothetical protein; InterPro IPR003390: IPR012505; KEGG: dal:Dalk_0397 protein of unknown function DUF147; PFAM: protein of unknown function DUF147; YbbR family protein; SPTR: Putative uncharacterized protein; PFAM: DisA bacterial checkpoint controller nucleotide-binding; TIGRFAM: conserved hypothetical protein TIGR00159.
  
 
 0.788
ADW17105.1
COGs: COG0294 Dihydropteroate synthase; InterPro IPR000489: IPR006390; KEGG: dak:DaAHT2_0903 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase.
 
  
 0.786
ADW17224.1
YbbR family protein; InterPro IPR012505; KEGG: dps:DP1640 hypothetical protein; PFAM: YbbR family protein; SPTR: YbbR-like; PFAM: YbbR-like protein.
  
  
 0.679
ADW16721.1
COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR006375: IPR005835: IPR001538; KEGG: bam:Bamb_0755 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-1-phosphate guanylyltransferase (GDP); TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase.
  
  
 0.619
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
 
  
 0.612
ADW17200.1
Nucleotidyl transferase; COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR005835; KEGG: dps:DP2941 mannose-1-phosphate guanylyltransferase; PFAM: Nucleotidyl transferase; SPTR: Nucleotidyl transferase; PFAM: Nucleotidyl transferase.
 
  
 0.597
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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