Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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ADW17233.1COGs: COG1570 Exonuclease VII large subunit; InterPro IPR004365: IPR020579: IPR003753: IPR018106; KEGG: dak:DaAHT2_0719 exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII, large subunit-like; nucleic acid binding OB-fold tRNA/helicase-type; SPTR: Exodeoxyribonuclease VII, large subunit; TIGRFAM: exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII, large subunit; OB-fold nucleic acid binding domain; TIGRFAM: exodeoxyribonuclease VII, large subunit. (462 aa)    
Predicted Functional Partners:
ADW18549.1
InterPro IPR003761; KEGG: dps:DP2698 exodeoxyribonuclease VII small subunit; PFAM: Exonuclease VII small subunit; SPTR: Exodeoxyribonuclease 7 small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit.
 
 0.998
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
 
    0.924
fliG
COGs: COG1536 Flagellar motor switch protein; InterPro IPR000090; KEGG: dps:DP2657 flagellar motor switch protein (FliG); PFAM: flagellar motor switch protein FliG; SPTR: Related to flagellar motor switch protein (FliG); TIGRFAM: flagellar motor switch protein FliG; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG.
   
   0.702
ADW18548.1
COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dps:DP2699 geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Probable geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase.
 
  
 0.635
ADW17909.1
COGs: COG0605 Superoxide dismutase; InterPro IPR019831: IPR019832: IPR001189: IPR019833; KEGG: efa:EF0463 superoxide dismutase, Mn; PFAM: Manganese/iron superoxide dismutase-like; PRIAM: Superoxide dismutase; SPTR: Superoxide dismutase; PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain.
      0.619
ADW16851.1
COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; InterProIPR013849: IPR000445: IPR011114: IPR000085: IPR 003583; KEGG: dak:DaAHT2_1207 Holliday junction DNA helicase RuvA; PFAM: DNA recombination protein RuvA domain I; helix-hairpin-helix motif; RuvA domain protein; SPTR: Holliday junction DNA helicase RuvA; TIGRFAM: Holliday junction DNA helicase RuvA; manually curated; PFAM: RuvA, C-terminal domain; RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit.
 
   
 0.568
ADW17080.1
COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); InterProIPR003594: IPR013507: IPR014790: IPR020667: IPR 014763; KEGG: dak:DaAHT2_1338 DNA mismatch repair protein MutL; PFAM: MutL dimerisation; DNA mismatch repair protein domain protein; ATP-binding region ATPase domain protein; SPTR: DNA mismatch repair protein MutL; TIGRFAM: DNA mismatch repair protein MutL; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; MutL C terminal dimerisation domain; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL.
 
   
 0.557
ADW18409.1
COGs: COG0556 Helicase subunit of the DNA excision repair complex; InterProIPR001943: IPR014021: IPR001650: IPR014001: IPR 004807: IPR006935; KEGG: dps:DP2765 excinuclease ABC subunit B; PFAM: helicase domain protein; type III restriction protein res subunit; UvrB/UvrC protein; SMART: DEAD-like helicase; helicase domain protein; SPTR: UvrABC system protein B; TIGRFAM: excinuclease ABC, B subunit; PFAM: Helicase conserved C-terminal domain; UvrB/uvrC motif; Type III restriction enzyme, res subunit; Ultra-violet resistance protein B; TIGRFAM: excinuclease ABC, B subunit.
 
  
 0.541
ADW16845.1
Sigma 54 interacting domain protein; COGs: COG0497 ATPase involved in DNA repair; InterPro IPR003395: IPR004604: IPR002078; KEGG: dak:DaAHT2_0696 DNA repair protein RecN; PFAM: SMC domain protein; SPTR: DNA repair protein RecN; TIGRFAM: DNA repair protein RecN; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN.
 
   
 0.539
ADW16628.1
COGs: COG0322 Nuclease subunit of the excinuclease complex; InterProIPR004791: IPR001943: IPR000305: IPR001162: IPR 000445: IPR003583; KEGG: dps:DP2478 excinuclease ABC subunit C; PFAM: excinuclease ABC C subunit domain protein; Excinuclease ABC C subunit domain protein; UvrB/UvrC protein; helix-hairpin-helix motif; SMART: Excinuclease ABC C subunit domain protein; Helix-hairpin-helix DNA-binding class 1; SPTR: UvrABC system protein C; TIGRFAM: excinuclease ABC, C subunit; manually curated; PFAM: UvrB/uvrC motif; UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; Helix-hair [...]
  
  
 0.534
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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