Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ADW17237.1Protein of unknown function DUF548; InterPro IPR007536; KEGG: tgr:Tgr7_1199 hypothetical protein; PFAM: protein of unknown function DUF548; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF548). (261 aa)    
Predicted Functional Partners:
ADW18769.1
Protein of unknown function DUF37; COGs: COG0759 conserved hypothetical protein; InterPro IPR002696; KEGG: rxy:Rxyl_3214 hypothetical protein; PFAM: protein of unknown function DUF37; SPTR: UPF0161 protein Rxyl_3214; manually curated; PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein YidD.
  
    0.752
ADW18270.1
COGs: COG0669 Phosphopantetheine adenylyltransferase; InterPro IPR001980: IPR004821: IPR004820; KEGG: cvi:CV_1103 phosphopantetheine adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: Phosphopantetheine adenylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain.
 
  
 0.730
ADW18676.1
COGs: COG0669 Phosphopantetheine adenylyltransferase; InterPro IPR001980: IPR004821: IPR004820; KEGG: dak:DaAHT2_0546 pantetheine-phosphate adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: Coenzyme A biosynthesis protein:Cytidyltransferase-related; TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain.
  
  
 0.654
ADW16633.1
Undecaprenyl-diphosphatase; COGs: COG1968 Uncharacterized bacitracin resistance protein; InterPro IPR003824; KEGG: azo:azo0712 undecaprenyl pyrophosphate phosphatase; PFAM: Bacitracin resistance protein BacA; SPTR: Undecaprenol kinase; TIGRFAM: undecaprenol kinase; PFAM: Bacitracin resistance protein BacA; TIGRFAM: undecaprenyl-diphosphatase UppP.
 
    0.619
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
  
    0.586
ADW17239.1
Protein of unknown function UPF0052 and CofD; COGs: COG0391 conserved hypothetical protein; InterPro IPR002882; KEGG: dak:DaAHT2_0940 protein of unknown function UPF0052 and CofD; PFAM: protein of unknown function UPF0052 and CofD; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0052; TIGRFAM: conserved hypothetical protein, cofD-related.
       0.501
ADW17240.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR004358: IPR005467: IPR001789: IPR003661: IPR 003594: IPR013656; KEGG: dak:DaAHT2_2582 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-l [...]
       0.467
ADW17241.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sat:SYN_00173 response regulator receiver domain-containing protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver domain; PFAM: Response regulator receiver domain.
       0.457
ADW17242.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 003594: IPR013656; KEGG: dak:DaAHT2_2397 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protei [...]
       0.457
ADW17264.1
Carbohydrate kinase, YjeF related protein; COGs: COG0063 sugar kinase; InterPro IPR000631: IPR004443: IPR017953; KEGG: dak:DaAHT2_0242 carbohydrate kinase, YjeF related protein; PFAM: YjeF-family domain-containing protein; protein of unknown function UPF0031; SPTR: Carbohydrate kinase, YjeF related protein; TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; Carbohydrate kinase; TIGRFAM: yjeF N-terminal region; yjeF C-terminal region, hydroxyethylthiazole kinase-related.
     
 0.436
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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