Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADW17239.1Protein of unknown function UPF0052 and CofD; COGs: COG0391 conserved hypothetical protein; InterPro IPR002882; KEGG: dak:DaAHT2_0940 protein of unknown function UPF0052 and CofD; PFAM: protein of unknown function UPF0052 and CofD; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0052; TIGRFAM: conserved hypothetical protein, cofD-related. (783 aa)    
Predicted Functional Partners:
ADW17242.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR004358: IPR005467: IPR001789: IPR000014: IPR 003594: IPR013656; KEGG: dak:DaAHT2_2397 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protei [...]
       0.782
ADW17240.1
COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR004358: IPR005467: IPR001789: IPR003661: IPR 003594: IPR013656; KEGG: dak:DaAHT2_2582 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: PAS/PAC sensor hybrid histidine kinase; PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-l [...]
       0.773
ADW17241.1
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: sat:SYN_00173 response regulator receiver domain-containing protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver domain; PFAM: Response regulator receiver domain.
       0.773
ADW19038.1
KEGG: dps:DP0068 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1566).
  
     0.761
ADW17057.1
Peptidoglycan glycosyltransferase; COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264: IPR001460: IPR003029; KEGG: dps:DP1675 penicillin-binding protein 1A; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Glycosyl transferase, family 51; PFAM: Transglycosylase.
 
   
 0.734
ADW16924.1
InterPro IPR002059: IPR011129; KEGG: dps:DP1086 cold-shock protein; PFAM: Cold-shock protein DNA-binding; SMART: Cold shock protein; SPTR: Similar to cold-shock protein; PFAM: 'Cold-shock' DNA-binding domain; Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein.
  
    0.727
ADW16234.1
KEGG: dak:DaAHT2_1493 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.719
ADW18146.1
Amidohydrolase; InterPro IPR006680; KEGG: dak:DaAHT2_2427 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family.
  
     0.690
ADW18324.1
COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR003099: IPR002912; KEGG: dps:DP2275 P-protein; PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; Prephenate dehydrogenase; SPTR: Related to P-protein; PFAM: Prephenate dehydratase; Prephenate dehydrogenase; ACT domain.
  
     0.687
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
       0.682
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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