Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADW17256.1GTP-binding protein Obg/CgtA; COGs: COG0536 GTPase; InterProIPR006073: IPR014100: IPR006169: IPR002917: IPR 006074: IPR005225; KEGG: dps:DP2590 GTPase ObgE; PFAM: GTP1/OBG sub domain protein; GTP-binding protein HSR1-related; SPTR: GTPase obg; TIGRFAM: GTP-binding protein Obg/CgtA; small GTP-binding protein; PFAM: GTPase of unknown function; GTP1/OBG; TIGRFAM: Obg family GTPase CgtA; small GTP-binding protein domain. (342 aa)    
Predicted Functional Partners:
rpmA
COGs: COG0211 Ribosomal protein L27; InterPro IPR001684; KEGG: dps:DP2591 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
 
 
 0.971
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
 
 
 0.959
rplT
LSU ribosomal protein L20P; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
 
 
 0.956
ADW18617.1
Pseudouridine synthase, RluA family; COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR002942: IPR006225: IPR006224: IPR006145; KEGG: dps:DP2730 ribosomal large subunit pseudouridine synthase D; PFAM: pseudouridine synthase; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family.
 
 
 0.917
ADW16667.1
Radical SAM domain protein; COGs: COG0731 Fe-S oxidoreductase; InterPro IPR007197; KEGG: dak:DaAHT2_2249 radical SAM domain protein; PFAM: Radical SAM domain protein; SPTR: Radical SAM domain protein; PFAM: Radical SAM superfamily.
 
 
    0.887
ADW17062.1
COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: dps:DP2618 hypothetical protein; PFAM: Iojap-related protein; SPTR: Putative uncharacterized protein; TIGRFAM: iojap-like protein; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein.
  
 
 0.886
rplA
LSU ribosomal protein L1P; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
  
 
 0.880
rplS
LSU ribosomal protein L19P; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
 
 
 0.878
ADW17257.1
COGs: COG0263 Glutamate 5-kinase; InterProIPR001057: IPR002478: IPR011529: IPR001048: IPR 019797: IPR005715; KEGG: dak:DaAHT2_1156 glutamate 5-kinase; PFAM: aspartate/glutamate/uridylate kinase; PUA domain containing protein; SMART: PUA domain containing protein; SPTR: Glutamate 5-kinase; TIGRFAM: glutamate 5-kinase; PFAM: PUA domain; Amino acid kinase family; TIGRFAM: glutamate 5-kinase.
  
  
 0.871
rplK
LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
  
 
 0.857
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: low (16%) [HD]