STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17257.1COGs: COG0263 Glutamate 5-kinase; InterProIPR001057: IPR002478: IPR011529: IPR001048: IPR 019797: IPR005715; KEGG: dak:DaAHT2_1156 glutamate 5-kinase; PFAM: aspartate/glutamate/uridylate kinase; PUA domain containing protein; SMART: PUA domain containing protein; SPTR: Glutamate 5-kinase; TIGRFAM: glutamate 5-kinase; PFAM: PUA domain; Amino acid kinase family; TIGRFAM: glutamate 5-kinase. (391 aa)    
Predicted Functional Partners:
ADW17258.1
Glutamate-5-semialdehyde dehydrogenase; COGs: COG0014 Gamma-glutamyl phosphate reductase; InterPro IPR012134: IPR015590: IPR020593: IPR000965; KEGG: dak:DaAHT2_1155 gamma-glutamyl phosphate reductase; PFAM: Aldehyde Dehydrogenase; SPTR: Gamma-glutamyl phosphate reductase; TIGRFAM: gamma-glutamyl phosphate reductase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: gamma-glutamyl phosphate reductase.
 
 0.999
ADW17738.1
COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR000304: IPR004455; KEGG: gme:Gmet_0899 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase.
 
 0.940
ADW17256.1
GTP-binding protein Obg/CgtA; COGs: COG0536 GTPase; InterProIPR006073: IPR014100: IPR006169: IPR002917: IPR 006074: IPR005225; KEGG: dps:DP2590 GTPase ObgE; PFAM: GTP1/OBG sub domain protein; GTP-binding protein HSR1-related; SPTR: GTPase obg; TIGRFAM: GTP-binding protein Obg/CgtA; small GTP-binding protein; PFAM: GTPase of unknown function; GTP1/OBG; TIGRFAM: Obg family GTPase CgtA; small GTP-binding protein domain.
  
  
 0.871
ADW19022.1
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: cja:CJA_3147 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
     
 0.806
ADW17259.1
COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; InterPro IPR004820: IPR005248: IPR004821; KEGG: dak:DaAHT2_1154 nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Nicotinate (Nicotinamide) nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain.
     
 0.673
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
 
  
 
 0.661
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
     
 0.656
rpmA
COGs: COG0211 Ribosomal protein L27; InterPro IPR001684; KEGG: dps:DP2591 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
     
 0.656
ADW17261.1
Hpt sensor hybrid histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358: IPR005467: IPR001789: IPR008207: IPR 003661: IPR003594; KEGG: pth:PTH_2386 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SPTR: Signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; [...]
  
   0.577
ADW17166.1
Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR002701: IPR001086: IPR008242: IPR020822: IPR 002912: IPR018528; KEGG: dps:DP2171 P-protein; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Probable P-protein; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
 
  
 0.546
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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