Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ADW17257.1COGs: COG0263 Glutamate 5-kinase; InterProIPR001057: IPR002478: IPR011529: IPR001048: IPR 019797: IPR005715; KEGG: dak:DaAHT2_1156 glutamate 5-kinase; PFAM: aspartate/glutamate/uridylate kinase; PUA domain containing protein; SMART: PUA domain containing protein; SPTR: Glutamate 5-kinase; TIGRFAM: glutamate 5-kinase; PFAM: PUA domain; Amino acid kinase family; TIGRFAM: glutamate 5-kinase. (391 aa)    
Predicted Functional Partners:
ADW17258.1
Glutamate-5-semialdehyde dehydrogenase; COGs: COG0014 Gamma-glutamyl phosphate reductase; InterPro IPR012134: IPR015590: IPR020593: IPR000965; KEGG: dak:DaAHT2_1155 gamma-glutamyl phosphate reductase; PFAM: Aldehyde Dehydrogenase; SPTR: Gamma-glutamyl phosphate reductase; TIGRFAM: gamma-glutamyl phosphate reductase; PFAM: Aldehyde dehydrogenase family; TIGRFAM: gamma-glutamyl phosphate reductase.
 
 0.999
ADW17738.1
COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR000304: IPR004455; KEGG: gme:Gmet_0899 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase.
 
 0.941
ADW17256.1
GTP-binding protein Obg/CgtA; COGs: COG0536 GTPase; InterProIPR006073: IPR014100: IPR006169: IPR002917: IPR 006074: IPR005225; KEGG: dps:DP2590 GTPase ObgE; PFAM: GTP1/OBG sub domain protein; GTP-binding protein HSR1-related; SPTR: GTPase obg; TIGRFAM: GTP-binding protein Obg/CgtA; small GTP-binding protein; PFAM: GTPase of unknown function; GTP1/OBG; TIGRFAM: Obg family GTPase CgtA; small GTP-binding protein domain.
  
  
 0.871
ADW17259.1
COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; InterPro IPR004820: IPR005248: IPR004821; KEGG: dak:DaAHT2_1154 nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Nicotinate (Nicotinamide) nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain.
     
 0.681
rpmA
COGs: COG0211 Ribosomal protein L27; InterPro IPR001684; KEGG: dps:DP2591 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
     
 0.667
rplU
LSU ribosomal protein L21P; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
     
 0.631
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
 
    
 0.624
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.578
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.571
ADW17166.1
Chorismate mutase; COGs: COG0077 Prephenate dehydratase; InterProIPR002701: IPR001086: IPR008242: IPR020822: IPR 002912: IPR018528; KEGG: dps:DP2171 P-protein; PFAM: prephenate dehydratase; Chorismate mutase, type II; amino acid-binding ACT domain protein; SPTR: Probable P-protein; PFAM: Prephenate dehydratase; ACT domain; Chorismate mutase type II.
 
  
 0.568
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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