STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17276.15-oxoprolinase (ATP-hydrolyzing); COGs: COG0146 N-methylhydantoinase B/acetone carboxylase alpha subunit; InterPro IPR008040: IPR002821: IPR003692: IPR019825; KEGG: bpt:Bpet2239 5-oxoprolinase; PFAM: Hydantoinase B/oxoprolinase; Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; PRIAM: 5-oxoprolinase (ATP-hydrolyzing); SPTR: Hydantoinase/oxoprolinase domain family protein; PFAM: Hydantoinase/oxoprolinase; Hydantoinase B/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region. (1214 aa)    
Predicted Functional Partners:
ADW16736.1
Hydantoinaseoxoprolinase domain protein; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040: IPR002821; KEGG: dps:DP0921 hydantoin utilization protein A; PFAM: Hydantoinaseoxoprolinase domain protein; Hydantoinase/oxoprolinase; SPTR: Related to hydantoin utilization protein A; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region.
 
 
0.909
ADW18278.1
Hydantoinase/oxoprolinase; COGs: COG0145 N-methylhydantoinase A/acetone carboxylase beta subunit; InterPro IPR008040: IPR002821; KEGG: dba:Dbac_0779 hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinaseoxoprolinase domain protein; SPTR: Hydantoinase/oxoprolinase; PFAM: Hydantoinase/oxoprolinase; Hydantoinase/oxoprolinase N-terminal region.
 
 
0.905
ADW18912.1
COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097: IPR006096: IPR006095; KEGG: dsa:Desal_1512 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: Glutamate dehydrogenase (NADP(+)); PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain.
    
 0.851
ADW19022.1
Glutamate synthase (NADPH) large subunit; COGs: COG0069 Glutamate synthase domain 2; InterProIPR017932: IPR000583: IPR006982: IPR002932: IPR 002489; KEGG: cja:CJA_3147 glutamate synthase subunit alpha; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase alpha subunit domain protein; PRIAM: Glutamate synthase (ferredoxin); SPTR: Glutamate synthase large chain; PFAM: Conserved region in glutamate synthase; GXGXG motif; Glutamate synthase central domain; Glutamine amidotransferases class-II.
    
 0.846
ADW17070.1
COGs: COG0069 Glutamate synthase domain 2; InterPro IPR002932: IPR017900: IPR017896; KEGG: dps:DP2623 glutamate synthase, alpha subunit; PFAM: ferredoxin-dependent glutamate synthase; SPTR: Related to glutamate synthase, alpha subunit; PFAM: 4Fe-4S binding domain; Conserved region in glutamate synthase.
  
 
  0.817
glnA
COGs: COG0174 Glutamine synthetase; InterPro IPR004809: IPR008147: IPR008146; KEGG: dat:HRM2_45740 GlnA2; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; PRIAM: Glutamate--ammonia ligase; SPTR: Glutamine synthetase; TIGRFAM: glutamine synthetase, type I; PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase, beta-Grasp domain; TIGRFAM: glutamine synthetase, type I.
     
  0.800
ADW18055.1
Glutamate synthase (NADPH) small subunit; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR000759: IPR013027; KEGG: dak:DaAHT2_1893 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric.
     
  0.800
ADW18275.1
Sulfide dehydrogenase (flavoprotein) subunit SudA; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR006004: IPR017896; KEGG: sat:SYN_00606 glutamate synthase (NADPH); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH); TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric.
     
  0.800
ADW19021.1
Glutamate synthase (NADPH) small subunit; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027: IPR000759: IPR006006; KEGG: maq:Maqu_0835 glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Glutamate synthase (NADPH) small subunit; TIGRFAM: glutamate synthase, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase small subunit family protein, proteobacterial.
     
  0.800
ADW17277.1
Rhodanese domain protein; COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001763; KEGG: dak:DaAHT2_0193 rhodanese domain protein; SMART: Rhodanese domain protein; SPTR: Rhodanese domain protein; PFAM: Metallo-beta-lactamase superfamily; Rhodanese-like domain.
       0.461
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: medium (44%) [HD]