STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17298.1Transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR001808: IPR000595: IPR012318; KEGG: dol:Dole_2102 Crp/FNR family transcriptional regulator; PFAM: cyclic nucleotide-binding; regulatory protein Crp; SMART: cyclic nucleotide-binding; regulatory protein Crp; SPTR: Transcriptional regulator, Crp/Fnr family; PFAM: Bacterial regulatory proteins, crp family; Cyclic nucleotide-binding domain. (222 aa)    
Predicted Functional Partners:
ADW18966.1
Adenylate/guanylate cyclase with GAF sensor(s); COGs: COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054: IPR003018; KEGG: dal:Dalk_4220 adenylate/guanylate cyclase with GAF sensor(s); PFAM: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SMART: GAF domain protein; adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: Adenylate/guanylate cyclase with GAF sensor(S); manually curated; PFAM: Adenylate and Guanylate cyclase catalytic domain; GAF domain.
 
 0.869
ADW18844.1
MIP family channel protein; COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425: IPR012269; KEGG: cli:Clim_1151 MIP family channel protein; PFAM: major intrinsic protein; SPTR: MIP family channel protein; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins.
   
 0.756
ADW17526.1
preQ(0) biosynthesis protein QueD; COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: dak:DaAHT2_0938 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; PFAM: 6-pyruvoyl tetrahydropterin synthase and hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein.
    
  0.752
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.684
ADW18355.1
Putative transcriptional regulator, Crp/Fnr family; COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595: IPR002373: IPR018488; KEGG: dal:Dalk_3876 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain.
  
   
 0.682
ADW16898.1
Adenylate/guanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR001789: IPR001054: IPR018297; KEGG: bja:blr2288 two-component hybrid sensor and regulator; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; SPTR: Adenylate/guanylate cyclase; PFAM: Adenylate and Guanylate cyclase catalytic domain; Response regulator receiver domain.
  
 0.670
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.665
ADW17363.1
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198: IPR020904; KEGG: tgr:Tgr7_2595 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
   
 0.654
ADW18159.1
3-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198: IPR020904: IPR011284; KEGG: dps:DP2790 3-oxoacyl-[acyl-carrier protein] reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Probable 3-oxoacyl-[acyl-carrier protein] reductase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase.
   
 0.654
ADW18638.1
Short-chain dehydrogenase/reductase SDR; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347: IPR002198; KEGG: dol:Dole_2622 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase.
   
 0.654
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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