STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADW17355.1Uncharacterized protein family UPF0066; COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: sfu:Sfum_1908 hypothetical protein; PFAM: Uncharacterised protein family UPF0066; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: probable methyltransferase, YaeB/AF_0241 family. (135 aa)    
Predicted Functional Partners:
ADW17356.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG2202 FOG: PAS/PAC domain; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 001610: IPR003594: IPR013767: IPR013656: IPR003661; KEGG: ppd:Ppro_2089 PAS/PAC sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: PAS/PAC sensor hybrid histidine kinase; [...]
       0.737
ADW16810.1
COGs: COG1237 Metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: pca:Pcar_1589 beta-lactamase superfamily hydrolase; SPTR: Metal-dependent hydrolase of the beta-lactamase superfamily II; PFAM: Metallo-beta-lactamase superfamily.
 
     0.436
ADW17357.1
Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: nhl:Nhal_2115 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family.
       0.421
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.