STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
ADW17357.1Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: nhl:Nhal_2115 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family. (179 aa)    
Predicted Functional Partners:
ADW17942.1
Heat shock protein Hsp20; COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: dak:DaAHT2_0432 heat shock protein HSP20; PFAM: heat shock protein Hsp20; SPTR: Heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family.
 
    0.815
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.681
clpA
ATP-dependent Clp protease ATP-binding subunit ClpA; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR004176: IPR003959: IPR013093: IPR019489: IPR 001270: IPR018368: IPR003593: IPR013461; KEGG: dak:DaAHT2_2492 ATP-dependent Clp protease, ATP-binding subunit ClpA; PFAM: ATPase AAA-2 domain protein; AAA ATPase central domain protein; Clp domain protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent Clp protease, ATP-binding subunit clpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA domain (Cdc48 subfamily); Clp amino termi [...]
  
 
 0.681
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.525
ADW17097.1
GrpE protein; COGs: COG0576 Molecular chaperone GrpE (heat shock protein); InterPro IPR000740; KEGG: dak:DaAHT2_0057 GrpE protein; PFAM: GrpE protein; SPTR: Protein grpE; PFAM: GrpE.
  
 
 0.479
ADW17358.1
COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006015: IPR006016; KEGG: dak:DaAHT2_2241 UspA domain protein; PFAM: UspA domain-containing protein; SPTR: UspA domain protein; PFAM: Universal stress protein family.
  
    0.479
ADW17356.1
PAS/PAC sensor hybrid histidine kinase; COGs: COG2202 FOG: PAS/PAC domain; InterProIPR005467: IPR001789: IPR000014: IPR000700: IPR 001610: IPR003594: IPR013767: IPR013656: IPR003661; KEGG: ppd:Ppro_2089 PAS/PAC sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; PAS fold domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: PAS/PAC sensor hybrid histidine kinase; [...]
       0.439
ADW17264.1
Carbohydrate kinase, YjeF related protein; COGs: COG0063 sugar kinase; InterPro IPR000631: IPR004443: IPR017953; KEGG: dak:DaAHT2_0242 carbohydrate kinase, YjeF related protein; PFAM: YjeF-family domain-containing protein; protein of unknown function UPF0031; SPTR: Carbohydrate kinase, YjeF related protein; TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; Carbohydrate kinase; TIGRFAM: yjeF N-terminal region; yjeF C-terminal region, hydroxyethylthiazole kinase-related.
 
    0.429
hslV
ATP dependent peptidase CodWX, CodW component; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.422
ADW17355.1
Uncharacterized protein family UPF0066; COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: sfu:Sfum_1908 hypothetical protein; PFAM: Uncharacterised protein family UPF0066; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: probable methyltransferase, YaeB/AF_0241 family.
       0.421
Your Current Organism:
Desulfobulbus propionicus
NCBI taxonomy Id: 577650
Other names: D. propionicus DSM 2032, Desulfobulbus propionicus DSM 2032, Desulfobulbus propionicus str. DSM 2032, Desulfobulbus propionicus strain DSM 2032
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